PT  - JOURNAL ARTICLE
AU  - Li-Li Wen
AU  - Xin Zhang
AU  - Qing-Rong Zhang
AU  - Qi Wu
AU  - Shu-Juan Chen
AU  - Jin-Long Deng
AU  - Kaiyi Huang
AU  - Han-Dong Wang
TI  - Flat-detector computed tomography PBV map in the evaluation of presurgical embolization for hypervascular brain tumors
AID  - 10.1136/neurintsurg-2016-012658
DP  - 2017 Nov 01
TA  - Journal of NeuroInterventional Surgery
PG  - 1139--1144
VI  - 9
IP  - 11
4099  - http://jnis.bmj.com/content/9/11/1139.short
4100  - http://jnis.bmj.com/content/9/11/1139.full
SO  - J NeuroIntervent Surg2017 Nov 01; 9
AB  - Background Preoperative embolization of hypervascular brain tumors is frequently used to minimize intraoperative bleeding.Objective To explore the efficacy of embolization using flat-detector CT (FDCT) parenchymal blood volume (PBV) maps before and after the intervention.Materials and methods Twenty-five patients with hypervascular brain tumors prospectively received pre- and postprocedural FDCT PBV scans using a biplane system under a protocol approved by the institutional research ethics committee. Semiquantitative analysis, based on region of interest measurements of the pre- and post-embolization PBV maps, operating time, and blood loss, was performed to assess the feasibility of PBV maps in detecting the perfusion deficit and to evaluate the efficacy of embolization.Results Preoperative embolization was successful in 18 patients. The relative PBV decreased significantly from 3.98±1.41 before embolization to 2.10±2.00 after embolization. Seventeen patients underwent surgical removal of tumors 24 hours after embolization. The post-embolic tumor perfusion index correlated significantly with blood loss (ρ=0.55) and operating time (ρ=0.60).Conclusions FDCT PBV mapping is a useful method for evaluating the perfusion of hypervascular brain tumors and the efficacy of embolization. It can be used as a supplement to CT perfusion, MRI, and DSA in the evaluation of tumor embolization.