RT Journal Article SR Electronic T1 Flat-detector computed tomography PBV map in the evaluation of presurgical embolization for hypervascular brain tumors JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 1139 OP 1144 DO 10.1136/neurintsurg-2016-012658 VO 9 IS 11 A1 Li-Li Wen A1 Xin Zhang A1 Qing-Rong Zhang A1 Qi Wu A1 Shu-Juan Chen A1 Jin-Long Deng A1 Kaiyi Huang A1 Han-Dong Wang YR 2017 UL http://jnis.bmj.com/content/9/11/1139.abstract AB Background Preoperative embolization of hypervascular brain tumors is frequently used to minimize intraoperative bleeding.Objective To explore the efficacy of embolization using flat-detector CT (FDCT) parenchymal blood volume (PBV) maps before and after the intervention.Materials and methods Twenty-five patients with hypervascular brain tumors prospectively received pre- and postprocedural FDCT PBV scans using a biplane system under a protocol approved by the institutional research ethics committee. Semiquantitative analysis, based on region of interest measurements of the pre- and post-embolization PBV maps, operating time, and blood loss, was performed to assess the feasibility of PBV maps in detecting the perfusion deficit and to evaluate the efficacy of embolization.Results Preoperative embolization was successful in 18 patients. The relative PBV decreased significantly from 3.98±1.41 before embolization to 2.10±2.00 after embolization. Seventeen patients underwent surgical removal of tumors 24 hours after embolization. The post-embolic tumor perfusion index correlated significantly with blood loss (ρ=0.55) and operating time (ρ=0.60).Conclusions FDCT PBV mapping is a useful method for evaluating the perfusion of hypervascular brain tumors and the efficacy of embolization. It can be used as a supplement to CT perfusion, MRI, and DSA in the evaluation of tumor embolization.