TY - JOUR T1 - Quantitative flow measurement after placing a flow diverter for a distal internal carotid artery aneurysm JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 1238 LP - 1242 DO - 10.1136/neurintsurg-2016-012730 VL - 9 IS - 12 AU - Chien-Wei Chen AU - Ho-Fai Wong AU - Yu-Ling Ye AU - Yao-Liang Chen AU - Wei-Liang Chen AU - Chang-Hsien Ou AU - Yuan-Hsiung Tsai Y1 - 2017/12/01 UR - http://jnis.bmj.com/content/9/12/1238.abstract N2 - Objectives To evaluate the differences in arterial flow after flow diverter placement using quantitative flow measurements based on digital subtraction angiography (DSA).Methods Between November 2013 and November 2015, all patients who had flow diverters placed for distal internal carotid artery (ICA) aneurysms were reviewed. Patients in whom the stent was placed across the ostia of the ophthalmic artery (OphA) and anterior choroidal artery (AChA) were enrolled. Five regions of interest were selected: the proximal ICA (as a reference), terminal ICA, middle cerebral artery (MCA), anterior cerebral artery (ACA), OphA, and AChA. The values of the peak, time-to-peak (TTP), and area under the curve (AUC) were analyzed using a quantitative DSA technique.Results The study enrolled 13 patients. The quantitative flow analysis showed improved flow in the terminal ICA (peak and AUC, p=0.036 and p=0.04, respectively), MCA (AUC, p=0.023), and ACA (AUC, p=0.006), and decreased flow in the OphA (peak and AUC, p=0.013 and p=0.005, respectively) and AChA (peak and subtracted TTP, p=0.023 and p=0.050, respectively) after flow diverter placement. Larger aneurysm volume was significantly correlated with decreased OphA flow after the procedure (peak and AUC, p=0.049 and p=0.037, respectively). Larger aneurysm volume also had a marginal correlation with increased distal ICA flow after the procedure, but this did not reach significance (peak and AUC, p=0.195 and p=0.060, respectively).Conclusions Without using extra contrast medium or radiation dosages, color-coded DSA enables quantitative monitoring of the cerebral circulation after flow-diverting treatment. ER -