TY - JOUR T1 - Commentary on ‘Curative cerebrovascular reconstruction with the Pipeline embolization device: the emergence of definitive endovascular therapy for intracranial aneurysms’ JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - i8 LP - i8 DO - 10.1136/neurintsurg-2018-014089 VL - 10 IS - Suppl 1 AU - Christophe Cognard Y1 - 2018/07/01 UR - http://jnis.bmj.com/content/10/Suppl_1/i8.abstract N2 - Before the era of mechanical thrombectomy for acute stroke, intracranial aneurysms were the major concern in endovascular surgery practice and research. Technology has been a key driver of the evolution of our field and the introduction of detachable GDC coils in 1992 can be considered as the birth of this new neuro-interventional discipline.1 Maturity came when the ISAT study, using an evidence-medicine approach, showed that endovascular therapy was equivalent to, or even better than, open surgery2.However, the limits of the endovascular discipline were obvious and they were often highlighted in the neurosurgical literature. These limits included the following issues: the majority of coiled aneurysms were not completely occluded at follow-up; up to one fifth … ER -