TY - JOUR T1 - WEB embolization versus stent-assisted coiling: comparison of complication rates and angiographic outcomes JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 812 LP - 816 DO - 10.1136/neurintsurg-2018-014555 VL - 11 IS - 8 AU - Christoph Kabbasch AU - Lukas Goertz AU - Eberhard Siebert AU - Moriz Herzberg AU - Jan Borggrefe AU - Boris Krischek AU - Pantelis Stavrinou AU - Franziska Dorn AU - Thomas Liebig Y1 - 2019/08/01 UR - http://jnis.bmj.com/content/11/8/812.abstract N2 - Background Intrasaccular flow disruption represents a new paradigm in endovascular treatment of wide-necked bifurcation aneurysms.Objective To perform a matched case–control study comparing complications and angiographic outcome using the Woven Endobridge (WEB) device and stent-assisted coiling (SAC).Methods Sixty-six patients treated with the WEB at three German tertiary care centers were included and matched with 66 patients treated with SAC based on aneurysm location and unruptured/ruptured aneurysm status. Parameters were retrospectively analysed and compared between the treatment groups using inverse probability of treatment weighting (IPTW) with propensity scores.Results Procedural complication rates were 12.1% in the WEB group and 21.2% in the SAC group, which was statistically significant after IPTW adjustment (OR=2.2, 95% CI 1.08 to 4.4, p=0.03). Favourable outcome (modified Rankin scale score ≤2) was achieved by 57/66 (86.4%) in the WEB group and 57/66 (86.4%) in the SAC group (p=1.0). At mid-term follow-up, a similar number of aneurysms achieved adequate occlusion (complete occlusion or neck remnant) in the WEB group (93.9%) and in the SAC group (93.9%, p=1.0). Re-treatment was performed in 10.6% after WEB embolization and 12.1% after SAC (p=1.0).Conclusions The WEB provides similar mid-term aneurysm occlusion rates to those of SAC, with no additional morbidity and potentially lower complication rates. Long-term outcome analysis will provide a definite conclusion on the use of WEB for intracranial aneurysms. ER -