RT Journal Article SR Electronic T1 Republished: Revisiting the therapeutic time window dogma: successful thrombectomy 6 days after stroke onset JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP e8 OP e8 DO 10.1136/neurintsurg-2018-014039.rep VO 11 IS 10 A1 Aguilar-Salinas, Pedro A1 Santos, Roberta A1 Granja, Manuel F A1 Effendi, Sabih A1 Sauvageau, Eric A1 Hanel, Ricardo A1 Aghaebrahim, Amin YR 2019 UL http://jnis.bmj.com/content/11/10/e8.abstract AB Stroke is the leading cause of serious long-term disability in the USA. Recent clinical trials, DAWN and DEFUSE 3, have expanded the endovascular therapeutic time window which has been adopted by the American Heart Association stroke guideline. However, there continues to be a dilemma as to what is the best approach for patients who present beyond the time window set by these trials and the current guideline. The interval from arterial occlusion to completion of brain tissue infarction varies from patient to patient and depends on the actual time and also a physiological clock or a tissue time window. Offering endovascular treatment based solely on a rigid time criterion excludes patients who may have a clinical benefit because of potentially salvageable tissue. We present a case of a patient who underwent successful stroke thrombectomy 6 days after stroke onset.