PT  - JOURNAL ARTICLE
AU  - Guilherme Barros
AU  - Abdullah H Feroze
AU  - Rajeev Sen
AU  - Cory M Kelly
AU  - Jason Barber
AU  - Danial K Hallam
AU  - Basavaraj Ghodke
AU  - Joshua W Osbun
AU  - Louis J Kim
AU  - Michael R Levitt
TI  - Predictors of preoperative endovascular embolization of meningiomas: subanalysis of anatomic location and arterial supply
AID  - 10.1136/neurintsurg-2019-015129
DP  - 2020 Feb 01
TA  - Journal of NeuroInterventional Surgery
PG  - 204--208
VI  - 12
IP  - 2
4099  - http://jnis.bmj.com/content/12/2/204.short
4100  - http://jnis.bmj.com/content/12/2/204.full
SO  - J NeuroIntervent Surg2020 Feb 01; 12
AB  - Introduction Endovascular embolization of intracranial meningiomas is commonly used as an adjunct to surgical resection. We sought to describe the anatomic locations and vascular supplies of meningiomas to identify characteristics predictive of successful preoperative endovascular embolization.Methods We conducted a retrospective review of 139 meningioma cases receiving cerebral angiograms for possible preoperative endovascular embolization at our institution between December 2000 and March 2017. The extent of embolization, arterial supply, anatomic location, and procedural complications were recorded for each case. Univariate and multivariate analyses were performed to identify tumor characteristics that predicted successful embolization.Results Of the total meningioma patients undergoing preoperative angiography, 78% (108/139) were successfully embolized, with a 2.8% periprocedural complication rate (3/108). Within the subset of patients with successful embolization, 31% (33/108) achieved complete angiographic embolization. Significant multivariate predictors of embolization (either partial or complete) were convexity/parasagittal locations (OR 5.15, 95% CI 0.93 to 28.54, p=0.060), meningohypophyseal trunk (MHT, OR 4.65, 95% CI 1.63 to 13.23, p=0.004), middle meningeal artery (MMA, OR 10.89, 95% CI 3.43 to 34.64, p<0.001), and ascending pharyngeal artery supply (APA, OR 9.96, 95% CI 1.88 to 52.73, p=0.007). Significant predictors for complete embolization were convexity/parasagittal locations (OR 4.79, 95% CI 1.66 to 13.84, p=0.004) and embolized APA supply (OR 6.94, 95% CI 1.90 to 25.39, p=0.003). Multiple arterial supply was a negative predictor of complete embolization (OR 0.38, 95% CI 0.15 to 0.98, p=0.05).Conclusions Tumor characteristics can be used to predict the likelihood of preoperative meningioma embolization. Parasagittal and convexity meningiomas, and those with APA supply, are most likely to achieve complete angiographic embolization.