@article {Kim315, author = {Sunghan Kim and Joonho Chung and Jihoon Cha and Byung Moon Kim and Dong Joon Kim and Yong Bae Kim and Jae Whan Lee and Seung Kon Huh and Keun Young Park}, title = {Usefulness of high-resolution three-dimensional proton density-weighted turbo spin-echo MRI in distinguishing a junctional dilatation from an intracranial aneurysm of the posterior communicating artery: a pilot study}, volume = {12}, number = {3}, pages = {315--319}, year = {2020}, doi = {10.1136/neurintsurg-2019-015149}, publisher = {British Medical Journal Publishing Group}, abstract = {Background Discriminating a junctional dilatation from a true saccular aneurysm is clinically important.Purpose To evaluate the usefulness of high-resolution three-dimensional proton density-weighted turbo spin-echo magnetic resonance imaging (PD MRI) in distinguishing a junctional dilatation from an aneurysm of the posterior communicating artery (PcomA).Methods Eighty-two consecutive patients with 83 PcomA lesions, which were evaluated by time-of-flight (TOF) MR angiography (MRA), PD MRI, and digital subtraction angiography (DSA), were enrolled. These radiologic data were retrospectively and independently reviewed by two neurosurgeons, and each diagnosis based on TOF MRA, PD MRI, and DSA was compared. The diagnostic efficacy (interobserver agreement, intermodality agreement, and diagnostic performance) of PD MRI was compared with that of TOF MRA.Results PD MRI showed higher AC1 (Gwet{\textquoteright}s agreement coefficient, PD MRI: 0.8942, 95\% CI 0.8204 to 0.968; TOF MRA: 0.7185, 95\% CI 0.5753 to 0.8617) and prevalence-adjusted bias-adjusted kappa coefficient (PABAK) (PD MRI: 0.8554, TOF MRA: 0.5904) than TOF MRA for interobserver agreement. For intermodality agreement, PD MRI also showed higher AC1 (PD MRI: 0.9069, 95\% CI 0.8374 to 0.9764; TOF MRA: 0.7983, 95\% CI 0.6969 to 0.8996) and PABAK (PD MRI: 0.8735, TOF MRA: 0.7289) than TOF MRA. The diagnostic performance of PD MRI was statistically superior to that of TOF MRA in sensitivity, specificity, positive predictive value, and negative predictive value.Conclusions PD MRI could provide excellent diagnostic accuracy and better information in distinguishing a junctional dilatation from a true saccular aneurysm of the PcomA compared with TOF MRA.}, issn = {1759-8478}, URL = {https://jnis.bmj.com/content/12/3/315}, eprint = {https://jnis.bmj.com/content/12/3/315.full.pdf}, journal = {Journal of NeuroInterventional Surgery} }