RT Journal Article SR Electronic T1 Delayed presentation of acute ischemic strokes during the COVID-19 crisis JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 639 OP 642 DO 10.1136/neurintsurg-2020-016299 VO 12 IS 7 A1 Clemens M Schirmer A1 Andrew J Ringer A1 Adam S Arthur A1 Mandy J Binning A1 W Christopher Fox A1 Robert F James A1 Michael R Levitt A1 Rabih G Tawk A1 Erol Veznedaroglu A1 Melanie Walker A1 Alejandro M Spiotta A1 , YR 2020 UL http://jnis.bmj.com/content/12/7/639.abstract AB Background The COVID-19 pandemic has disrupted established care paths worldwide. Patient awareness of the pandemic and executive limitations imposed on public life have changed the perception of when to seek care for acute conditions in some cases. We sought to study whether there is a delay in presentation for acute ischemic stroke patients in the first month of the pandemic in the US.Methods The interval between last-known-well (LKW) time and presentation of 710 consecutive patients presenting with acute ischemic strokes to 12 stroke centers across the US were extracted from a prospectively maintained quality database. We analyzed the timing and severity of the presentation in the baseline period from February to March 2019 and compared results with the timeframe of February and March 2020.Results There were 320 patients in the 2-month baseline period in 2019, there was a marked decrease in patients from February to March of 2020 (227 patients in February, and 163 patients in March). There was no difference in the severity of the presentation between groups and no difference in age between the baseline and the COVID period. The mean interval from LKW to the presentation was significantly longer in the COVID period (603±1035 min) compared with the baseline period (442±435 min, P<0.02).Conclusion We present data supporting an association between public awareness and limitations imposed on public life during the COVID-19 pandemic in the US and a delay in presentation for acute ischemic stroke patients to a stroke center.