RT Journal Article SR Electronic T1 Neuroanatomy of the middle cerebral artery: implications for thrombectomy JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 768 OP 773 DO 10.1136/neurintsurg-2019-015782 VO 12 IS 8 A1 Shapiro, Maksim A1 Raz, Eytan A1 Nossek, Erez A1 Chancellor, Breehan A1 Ishida, Koto A1 Nelson, Peter Kim YR 2020 UL http://jnis.bmj.com/content/12/8/768.abstract AB Our perspective on anatomy frequently depends on how this anatomy is utilized in clinical practice, and by which methods knowledge is acquired. The thrombectomy revolution, of which the middle cerebral artery (MCA) is the most common target, is an example of a clinical paradigm shift with a unique perspective on cerebrovascular anatomy. This article reviews important features of MCA anatomy in the context of thrombectomy. Recognizing that variation, frequently explained by evolutionary concepts, is the rule when it comes to branching pattern, vessel morphology, territory, or collateral potential is key to successful thrombectomy strategy.