PT  - JOURNAL ARTICLE
AU  - Wei-dong Xu
AU  - Han Wang
AU  - Qi Wu
AU  - Li-Li Wen
AU  - Zong-qi You
AU  - Bin Yuan
AU  - Shu-juan Chen
AU  - Han-Dong Wang
AU  - Xin Zhang
TI  - Morphology parameters for rupture in middle cerebral artery mirror aneurysms
AID  - 10.1136/neurintsurg-2019-015620
DP  - 2020 Sep 01
TA  - Journal of NeuroInterventional Surgery
PG  - 858--861
VI  - 12
IP  - 9
4099  - http://jnis.bmj.com/content/12/9/858.short
4100  - http://jnis.bmj.com/content/12/9/858.full
SO  - J NeuroIntervent Surg2020 Sep 01; 12
AB  - Objective To identify the morphological parameters correlated with the rupture of middle cerebral artery (MCA) aneurysms.Methods We retrospectively analyzed the digital subtraction angiography (DSA) data of 48 patients with ruptured mirror MCA aneurysms. Morphological parameters included aneurysm with wall protrusion, maximum diameter (Dmax), height, neck width, aneurysm width, dome projection, parent artery average diameter (Dp), aspect ratio (AR), bottleneck factor (BNF), size ratio (SR), M1/M2 ratio, and height/width (H/W) ratio. These paired parameters were analyzed by conditional univariate and multivariate logistic regressions to screen out the independent risk factors. We established a score based on the independent risk factors. Receiver operating characteristics (ROC) were generated to estimate the prediction performance of the score in our large database of 763 aneurysms.Results In the univariate regressions, Dmax, height, aneurysm width, neck width, AR, BNF, H/W ratio, SR, anterior dome projection and aneurysm with wall protrusion were significant risk factors. Aneurysm width (OR 3.296, p=0.015), AR (OR 11.594, p=0.014) and anterior dome projection (OR 9.385, p=0.016) were independent risk factors in multivariate regression. The area under the curve (AUC) value of the score based on the three independent risk factors was 0.829.Conclusion Aneurysm width, AR and anterior dome projection were independent risks factors of rupture.