RT Journal Article
SR Electronic
T1 Morphology parameters for rupture in middle cerebral artery mirror aneurysms
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP 858
OP 861
DO 10.1136/neurintsurg-2019-015620
VO 12
IS 9
A1 Wei-dong Xu
A1 Han Wang
A1 Qi Wu
A1 Li-Li Wen
A1 Zong-qi You
A1 Bin Yuan
A1 Shu-juan Chen
A1 Han-Dong Wang
A1 Xin Zhang
YR 2020
UL http://jnis.bmj.com/content/12/9/858.abstract
AB Objective To identify the morphological parameters correlated with the rupture of middle cerebral artery (MCA) aneurysms.Methods We retrospectively analyzed the digital subtraction angiography (DSA) data of 48 patients with ruptured mirror MCA aneurysms. Morphological parameters included aneurysm with wall protrusion, maximum diameter (Dmax), height, neck width, aneurysm width, dome projection, parent artery average diameter (Dp), aspect ratio (AR), bottleneck factor (BNF), size ratio (SR), M1/M2 ratio, and height/width (H/W) ratio. These paired parameters were analyzed by conditional univariate and multivariate logistic regressions to screen out the independent risk factors. We established a score based on the independent risk factors. Receiver operating characteristics (ROC) were generated to estimate the prediction performance of the score in our large database of 763 aneurysms.Results In the univariate regressions, Dmax, height, aneurysm width, neck width, AR, BNF, H/W ratio, SR, anterior dome projection and aneurysm with wall protrusion were significant risk factors. Aneurysm width (OR 3.296, p=0.015), AR (OR 11.594, p=0.014) and anterior dome projection (OR 9.385, p=0.016) were independent risk factors in multivariate regression. The area under the curve (AUC) value of the score based on the three independent risk factors was 0.829.Conclusion Aneurysm width, AR and anterior dome projection were independent risks factors of rupture.