TY - JOUR T1 - Endovascular versus surgical treatment for improvement of oculomotor nerve palsy caused by unruptured posterior communicating artery aneurysms JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 964 LP - 967 DO - 10.1136/neurintsurg-2020-015802 VL - 12 IS - 10 AU - Francesco Signorelli AU - Raoul Pop AU - Mario Ganau AU - Helene Cebula AU - Antonino Scibilia AU - Paolo Gallinaro AU - Ismail Zaed AU - Julien Todeschi AU - Etienne Lefevre AU - Beniamino Nannavecchia AU - Francois Severac AU - Hugo Andres Coca AU - Francis Turjman AU - Rodolfo Maduri AU - Rémy Beaujeux AU - Francois Proust AU - Salvatore Chibarro Y1 - 2020/10/01 UR - http://jnis.bmj.com/content/12/10/964.abstract N2 - Background There is no consensus regarding the best treatment option for unruptured aneurysms of the posterior communicating artery (PCom) presenting with oculomotor nerve palsy (ONP). We aimed to assess predictors of ONP recovery in a multicenter series of consecutive patients.Materials and methods A retrospective review of prospective databases in three tertiary neurosurgical centers was carried out, selecting patients with ONP caused by unruptured PCom aneurysms, treated by surgical clipping or embolization, between January 2006 and December 2013. Patient files and imaging studies were used to extract ophthalmological assessments, treatment outcomes, and follow-up data. Predictors of ONP recovery during follow-up were explored using univariate and multivariate analyses.Results We identified 55 patients with a median ONP duration before treatment of 11 days (IQR 4.5–18); the deficit was complete in 27 (49.1%) and incomplete in 28 (50.9%) cases. Median aneurysm size was 7 mm (IQR 5–9). Twenty-four (43.6%) patients underwent surgical clipping and 31 (56.4%) embolization as the primary treatment. Overall, ONP improved in 40 (72.7%) patients and persisted/recurred in 15 (27.3 %). Surgery, interval to complete treatment <4 weeks, aneurysm recurrence during follow-up, and retreatment during follow-up were significantly correlated with ONP outcome in the univariate analysis. In the multivariate analysis, independent predictors of ONP improvement were interval to complete treatment <4 weeks (OR 5.15, 95% CI 1.37 to 23.71, p=0.015) and aneurysm recurrence during follow-up (OR 0.1, 95% CI 0.02 to 0.47, p=0.003).Conclusion There was no significant difference in ONP recovery between surgical clipping and embolization. The best predictor for ONP recovery was timely, complete, and durable aneurysm exclusion. ER -