PT  - JOURNAL ARTICLE
AU  - Li, Yangchun
AU  - Chen, Stephanie H
AU  - Spiotta, Alejandro M
AU  - Jabbour, Pascal
AU  - Levitt, Michael R
AU  - Kan, Peter
AU  - Griessenauer, Christoph J
AU  - Arthur, Adam S
AU  - Osbun, Joshua W
AU  - Park, Min S
AU  - Chalouhi, Nohra
AU  - Sweid, Ahmad
AU  - Wolfe, Stacey Q
AU  - Fargen, Kyle M
AU  - Dumont, Aaron S
AU  - Dumont, Travis M
AU  - Brunet, Marie-Christine
AU  - Sur, Samir
AU  - Luther, Evan
AU  - Strickland, Allison
AU  - Yavagal, Dileep R
AU  - Peterson, Eric C
AU  - Schirmer, Clemens M
AU  - Goren, Oded
AU  - Dalal, Shamsher
AU  - Weiner, Gregory
AU  - Rosengart, Axel
AU  - Raper, Daniel
AU  - Chen, Ching-Jen
AU  - Amenta, Peter
AU  - Scullen, Tyler
AU  - Kelly, Cory Michael
AU  - Young, Christopher
AU  - Nahhas, Michael
AU  - Almallouhi, Eyad
AU  - Gunasekaran, Arunprasad
AU  - Pai, Suhas
AU  - Lanzino, Giuseppe
AU  - Brinjikji, Waleed
AU  - Abbasi, Mehdi
AU  - Dornbos III, David
AU  - Goyal, Nitin
AU  - Peterson, Jeremy
AU  - El-Ghanem, Mohammad H
AU  - Starke, Robert M
TI  - Lower complication rates associated with transradial versus transfemoral flow diverting stent placement
AID  - 10.1136/neurintsurg-2020-015992
DP  - 2021 Jan 01
TA  - Journal of NeuroInterventional Surgery
PG  - 91--95
VI  - 13
IP  - 1
4099  - http://jnis.bmj.com/content/13/1/91.short
4100  - http://jnis.bmj.com/content/13/1/91.full
SO  - J NeuroIntervent Surg2021 Jan 01; 13
AB  - Background Currently, there are no large-scale studies in the neurointerventional literature comparing safety between transradial (TRA) and transfemoral (TFA) approaches for flow diversion procedures. This study aims to assess complication rates in a large multicenter registry for TRA versus TFA flow diversion.Methods We retrospectively analyzed flow diversion cases for cerebral aneurysms from 14 institutions from 2010 to 2019. Pooled analysis of proportions was calculated using weighted analysis with 95% CI to account for results from multiple centers. Access site complication rate and overall complication rate were compared between the two approaches.Results A total of 2,285 patients who underwent flow diversion were analyzed, with 134 (5.86%) treated with TRA and 2151 (94.14%) via TFA. The two groups shared similar patient and aneurysm characteristics. Crossover from TRA to TFA was documented in 12 (8.63%) patients. There were no access site complications in the TRA group. There was a significantly higher access site complication rate in the TFA cohort as compared with TRA (2.48%, 95% CI 2.40% to 2.57%, vs 0%; p=0.039). One death resulted from a femoral access site complication. The overall complications rate was also higher in the TFA group (9.02%, 95% CI 8.15% to 9.89%) compared with the TRA group (3.73%, 95% CI 3.13% to 4.28%; p=0.035).Conclusion TRA may be a safer approach for flow diversion to treat cerebral aneurysms at a wide range of locations. Both access site complication rate and overall complication rate were lower for TRA flow diversion compared with TFA in this large series.