RT Journal Article
SR Electronic
T1 Lower complication rates associated with transradial versus transfemoral flow diverting stent placement
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP 91
OP 95
DO 10.1136/neurintsurg-2020-015992
VO 13
IS 1
A1 Li, Yangchun
A1 Chen, Stephanie H
A1 Spiotta, Alejandro M
A1 Jabbour, Pascal
A1 Levitt, Michael R
A1 Kan, Peter
A1 Griessenauer, Christoph J
A1 Arthur, Adam S
A1 Osbun, Joshua W
A1 Park, Min S
A1 Chalouhi, Nohra
A1 Sweid, Ahmad
A1 Wolfe, Stacey Q
A1 Fargen, Kyle M
A1 Dumont, Aaron S
A1 Dumont, Travis M
A1 Brunet, Marie-Christine
A1 Sur, Samir
A1 Luther, Evan
A1 Strickland, Allison
A1 Yavagal, Dileep R
A1 Peterson, Eric C
A1 Schirmer, Clemens M
A1 Goren, Oded
A1 Dalal, Shamsher
A1 Weiner, Gregory
A1 Rosengart, Axel
A1 Raper, Daniel
A1 Chen, Ching-Jen
A1 Amenta, Peter
A1 Scullen, Tyler
A1 Kelly, Cory Michael
A1 Young, Christopher
A1 Nahhas, Michael
A1 Almallouhi, Eyad
A1 Gunasekaran, Arunprasad
A1 Pai, Suhas
A1 Lanzino, Giuseppe
A1 Brinjikji, Waleed
A1 Abbasi, Mehdi
A1 Dornbos III, David
A1 Goyal, Nitin
A1 Peterson, Jeremy
A1 El-Ghanem, Mohammad H
A1 Starke, Robert M
YR 2021
UL http://jnis.bmj.com/content/13/1/91.abstract
AB Background Currently, there are no large-scale studies in the neurointerventional literature comparing safety between transradial (TRA) and transfemoral (TFA) approaches for flow diversion procedures. This study aims to assess complication rates in a large multicenter registry for TRA versus TFA flow diversion.Methods We retrospectively analyzed flow diversion cases for cerebral aneurysms from 14 institutions from 2010 to 2019. Pooled analysis of proportions was calculated using weighted analysis with 95% CI to account for results from multiple centers. Access site complication rate and overall complication rate were compared between the two approaches.Results A total of 2,285 patients who underwent flow diversion were analyzed, with 134 (5.86%) treated with TRA and 2151 (94.14%) via TFA. The two groups shared similar patient and aneurysm characteristics. Crossover from TRA to TFA was documented in 12 (8.63%) patients. There were no access site complications in the TRA group. There was a significantly higher access site complication rate in the TFA cohort as compared with TRA (2.48%, 95% CI 2.40% to 2.57%, vs 0%; p=0.039). One death resulted from a femoral access site complication. The overall complications rate was also higher in the TFA group (9.02%, 95% CI 8.15% to 9.89%) compared with the TRA group (3.73%, 95% CI 3.13% to 4.28%; p=0.035).Conclusion TRA may be a safer approach for flow diversion to treat cerebral aneurysms at a wide range of locations. Both access site complication rate and overall complication rate were lower for TRA flow diversion compared with TFA in this large series.