TY - JOUR T1 - Letter by Tang <em>et al</em> regarding the article ‘Leukoaraiosis and acute ischemic stroke: 90-day clinical outcome following endovascular recanalization, with proposed “L-ASPECTS”’ JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - e7 LP - e7 DO - 10.1136/neurintsurg-2020-016791 VL - 13 IS - 4 AU - Xiaojia Tang AU - Yuhan Luo AU - Peipei Liu AU - Yingzhu Chen Y1 - 2021/04/01 UR - http://jnis.bmj.com/content/13/4/e7.abstract N2 - We read with great interest the article by Bandaru et al 1 in a recent issue of the Journal of NeuroInterventional Surgery in which they have identified that leukoaraiosis (LA) severity on pre-mechanical thrombectomy (MT) no contrast computed tomography (NCCT) is associated with worse 90-day outcomes in patients with acute ischemic stroke (AIS) following endovascular recanalization, and is an independent risk factor for worse outcomes. Moreover, they proposed a modification to the ASPECT score, L-ASPECTS, which combines ischemia with white matter injury on the basis of the original ASPECTS.2 In the latest BEST trial study,3 Mistry et al found that patients with moderate-to-severe LA had … ER -