RT Journal Article SR Electronic T1 Efficacy of beveled tip aspiration catheter in mechanical thrombectomy for acute ischemic stroke JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 823 OP 826 DO 10.1136/neurintsurg-2020-016695 VO 13 IS 9 A1 Vargas, Jan A1 Blalock, Jonathan A1 Venkatraman, Anand A1 Anagnostakou, Vania A1 King, Robert M A1 Ewing, Joseph A A1 Gounis, Matthew J A1 Turner, Raymond D A1 Chaudry, Imran A1 Turk, Aquilla YR 2021 UL http://jnis.bmj.com/content/13/9/823.abstract AB Background Direct aspiration thrombectomy techniques use large bore aspiration catheters for mechanical thrombectomy. Several aspiration catheters are now available. We report a bench top exploration of a novel beveled tip catheter and our experience in treating large vessel occlusions (LVOs) using next-generation aspiration catheters.Methods A retrospective analysis from a prospectively maintained database comparing the bevel shaped tip aspiration catheter versus non-beveled tip catheters was performed. Patient demographics, periprocedural metrics, and discharge and 90-day modified Rankin Scale (mRS) scores were collected. Patients were divided into two groups based on which aspiration catheter was used.Results Our data showed no significant difference in age, gender, IV tissue plasminogen activator administration, admission NIH Stroke Scale score, baseline mRS, or LVO location between the beveled tip and flat tip groups. With the beveled tip, Thrombolysis in Cerebral Infarction (TICI) 2C or better recanalization was more frequent overall (93.2% vs 74.2%, p=0.017), stent retriever usage was lower (9.1% vs 29%, p=0.024), and patients had lower mRS on discharge (median 3 vs 4, p<0.001) and at 90 days (median 2 vs 4, p=0.008).Conclusion Patients who underwent mechanical thrombectomy with the beveled tip catheter had a higher proportion of TICI 2C or better and had a significantly lower mRS score on discharge and at 90 days.Data are available upon reasonable request. Please contact the corresponding author for data requests.