TY - JOUR T1 - Immediate post-operative aneurysm occlusion after endovascular treatment of intracranial aneurysms with coiling or balloon-assisted coiling in a prospective multicenter cohort of 1189 patients: Analysis of Recanalization after Endovascular Treatment of intracranial Aneurysm (ARETA) Study JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 918 LP - 923 DO - 10.1136/neurintsurg-2020-017012 VL - 13 IS - 10 AU - Laurent Pierot AU - Coralie Barbe AU - Denis Herbreteau AU - Jean-Yves Gauvrit AU - Anne-Christine Januel AU - Fouzi Bala AU - Frédéric Ricolfi AU - Hubert Desal AU - Stéphane Velasco AU - Mohamed Aggour AU - Emmanuel Chabert AU - Jacques Sedat AU - Denis Trystram AU - Gaultier Marnat AU - Sophie Gallas AU - Georges Rodesch AU - Frédéric Clarençon AU - Chrysanthi Papagiannaki AU - Phil White AU - Laurent Spelle A2 - , Y1 - 2021/10/01 UR - http://jnis.bmj.com/content/13/10/918.abstract N2 - Background Coiling, including balloon-assisted coiling (BAC), is the first-line therapy for ruptured and unruptured aneurysms. Its efficacy can be clinically evaluated by bleeding/rebleeding rate after coiling, and anatomically evaluated by aneurysm occlusion post-procedure and during follow-up. We aimed to analyze immediate post-coiling aneurysm occlusion and associated factors within the Analysis of Recanalization after Endovascular Treatment of intracranial Aneurysm (ARETA) population.Methods Between December 2013 and May 2015, 16 neurointerventional departments prospectively enrolled participants treated for ruptured and unruptured aneurysms (ClinicalTrials.gov: NCT01942512). Participant demographics, aneurysm characteristics, and endovascular techniques were recorded. In patients with aneurysms treated by coiling or BAC, immediate post-operative aneurysm occlusion was independently evaluated by a core lab using a 3-grade scale: complete occlusion, neck remnant, and aneurysm remnant.Results Of 1135 participants (age 53.8±12.8 years, 754 women (66.4%)), 1189 aneurysms were analyzed. Treatment modality was standard coiling in 645/1189 aneurysms (54.2%) and BAC in 544/1189 (45.8%). Immediate post-operative aneurysm occlusion was complete occlusion in 57.8%, neck remnant in 34.4%, and aneurysm remnant in 7.8%. Adequate occlusion (complete occlusion or neck remnant) was significantly more frequent in aneurysms with size <10 mm (93.1% vs 86.3%; OR 1.8, 95% CI 1.1 to 3.2; p=0.02) and in aneurysms with a narrow neck (95.8% vs 89.6%; OR 2.5, 95% CI 1.5 to 4.1; p=0.0004). Patients aged <70 years had significantly more adequate occlusion (92.7% vs 87.2%; OR 1.9, 95% CI 1.1 to 3.4; p=0.04).Conclusions Immediately after aneurysm coiling, including BAC, adequate aneurysm occlusion was obtained in 92.2%. Age <70 years, aneurysm size <10 mm, and narrow neck were factors associated with adequate occlusion.Trial registration number NCT01942512, http://www.clinicaltrials.gov.Data are available upon reasonable request. Data analyzed during the study are available from the corresponding author by request. ER -