TY - JOUR T1 - Woven EndoBridge device for ruptured aneurysms: perioperative results of a US multicenter experience JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 1012 LP - 1016 DO - 10.1136/neurintsurg-2020-017105 VL - 13 IS - 11 AU - Gustavo M Cortez AU - Erinc Akture AU - Andre Monteiro AU - Adam S Arthur AU - Jeremy Peterson AU - David Dornbos AU - Pascal Jabbour AU - M Reid Gooch AU - Ahmad Sweid AU - Stavropoula I Tjoumakaris AU - Josser E Delgado Almandoz AU - Yasha Kayan AU - Ansaar T Rai AU - SoHyun Boo AU - David Fiorella AU - Jay Vachhani AU - Paul Foreman AU - Marshall Cress AU - Adnan H Siddiqui AU - Muhammad Waqas AU - Amin Aghaebrahim AU - Eric Sauvageau AU - Ricardo A Hanel Y1 - 2021/11/01 UR - http://jnis.bmj.com/content/13/11/1012.abstract N2 - Background The Woven EndoBridge (WEB) device is approved in the USA for treatment of unruptured wide-neck bifurcation aneurysms. However, the safety and effectiveness of the WEB device in the treatment of ruptured intracranial aneurysms is not clear. We aim to evaluate the perioperative safety and effectiveness of the WEB device in patients with ruptured intracranial aneurysms.Methods This retrospective study, conducted at eight centers in the USA, included patients with ruptured intracranial aneurysms treated with the WEB device in the setting of subarachnoid hemorrhage (SAH). Safety outcomes included intraoperative complications such as vessel perforation, thromboembolic events, and postoperative hemorrhagic or thromboembolic complications based on radiologic imaging. The primary effectiveness outcome was adequate (complete and neck remnant) aneurysm occlusion, according to the Raymond–Roy classification.Results A total of 91 patients with 94 ruptured intracranial aneurysms were included (mean age 57.7±15.2 years; 68.1% women; 82.9% wide-necked). Aneurysms were located in the anterior communicating artery (42/94, 44.6%), middle cerebral artery (16/94, 17%), and basilar artery (15/94, 16%). Adequate occlusion was achieved in 48.8% (41/84) and 80.0% (40/50) at discharge and last follow-up (mean of 3.4 months), respectively. At discharge, procedural-related morbidity was 3.3% (3/91) and there was no procedure-related mortality. No re-rupture or delayed aneurysm rupture was observed.Conclusions This study demonstrates the perioperative safety and effectiveness of the WEB device for the treatment of patients with ruptured intracranial aneurysms in the setting of SAH, with low periprocedural morbidity and mortality. Long-term follow-up is warranted.Data are available upon reasonable request. ER -