RT Journal Article SR Electronic T1 WEB device for treatment of posterior communicating artery aneurysms JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP 362 OP 365 DO 10.1136/neurintsurg-2021-017405 VO 14 IS 4 A1 Aguiar, Guilherme A1 Caroff, Jildaz A1 Mihalea, Cristian A1 Cortese, Jonathan A1 Girot, Jean-Baptiste A1 Elawady, Ahmed A1 Vergara Martinez, Jeickson A1 Ikka, Léon A1 Gallas, Sophie A1 Chalumeau, Vanessa A1 Ozanne, Augustin A1 Moret, Jacques A1 Spelle, Laurent YR 2022 UL http://jnis.bmj.com/content/14/4/362.abstract AB Background Woven EndoBridge (WEB) device treatment of wide-neck bifurcation aneurysms has proved to be safe and effective, but the use of these devices in sidewall aneurysms has been reported only in a small number of case series.Objective To report our results in a cohort of consecutive patients in whom a WEB device was used as first-line treatment for posterior communicating artery (PComA) aneurysms.Methods We conducted a retrospective analysis of a prospectively maintained database of PComA aneurysms treated with a WEB device in our institution from June 1, 2012 to November 15, 2020. Clinical and radiological findings were evaluated at immediate and last follow-up.Results A total of 219 aneurysms were treated with a WEB device, including 15 PComA aneurysms in 15 patients, 10 of which were ruptured. Aneurysms were wide necked, with a mean aspect ratio of 1.6 (range 0.7–3.0) and a mean neck size of 4.2 mm (range 2.6–7.4 mm). No intraoperative rupture occurred and only one thromboembolic event was noted. Among the group with at least a 3-month digital subtraction angiography (DSA) follow-up, complete and adequate occlusion were obtained in 54% and 72%, respectively (average follow-up 13 months). Re-treatment was needed for two initially ruptured aneurysms. No procedure-related morbidity or mortality was reported.Conclusion This series suggests the high safety profile of WEB devices even when used in off-label indications. Treatment with these devices seems to be a valuable strategy for ruptured wide-neck PComA aneurysms, avoiding the need for antiplatelet medication. However, occlusion rates should be investigated in further larger studies.Data are available upon reasonable request.