PT  - JOURNAL ARTICLE
AU  - Alpay, Kemal
AU  - Hinkka, Tero
AU  - Lindgren, Antti E
AU  - Isokangas, Juha-Matti
AU  - Raj, Rahul
AU  - Parkkola, Riitta
AU  - Sinisalo, Matias
AU  - Numminen, Jussi
AU  - Pienimäki, Juha-Pekka
AU  - Saari, Petri
AU  - Seppänen, Janne
AU  - Palosaari, Kari
AU  - Rautio, Riitta
TI  - Finnish flow diverter study: 8 years of experience in the treatment of acutely ruptured intracranial aneurysms
AID  - 10.1136/neurintsurg-2021-017641
DP  - 2022 Jul 01
TA  - Journal of NeuroInterventional Surgery
PG  - 699--703
VI  - 14
IP  - 7
4099  - http://jnis.bmj.com/content/14/7/699.short
4100  - http://jnis.bmj.com/content/14/7/699.full
SO  - J NeuroIntervent Surg2022 Jul 01; 14
AB  - Background Flow diversion of acutely ruptured intracranial aneurysms (IAs) is controversial due to high treatment-related complication rates and a lack of supporting evidence. We present clinical and radiological results of the largest series to date.Methods This is a nationwide retrospective study of acutely ruptured IAs treated with flow diverters (FDs). The primary outcome was the modified Rankin Scale (mRS) score at the last available follow-up time. Secondary outcomes were treatment-related complications and the aneurysm occlusion rate.Results 110 patients (64 females; mean age 55.7 years; range 12–82 years) with acutely ruptured IAs were treated with FDs between 2012 and 2020 in five centers. 70 acutely ruptured IAs (64%) were located in anterior circulation, and 47 acutely ruptured IAs (43%) were blister-like. A favorable functional outcome (mRS 0–2) was seen in 73% of patients (74/102). Treatment-related complications were seen in 45% of patients (n=49). Rebleeding was observed in 3 patients (3%). The data from radiological follow-ups were available for 80% of patients (n=88), and complete occlusion was seen in 90% of aneurysms (79/88). The data from clinical follow-ups were available for 93% of patients (n=102). The overall mortality rate was 18% (18/102).Conclusions FD treatment yields high occlusion for acutely ruptured IAs but is associated with a high risk of complications. Considering the high mortality rate of aneurysmal subarachnoid hemorrhage, the prevention of rebleeding is crucial. Thus, FD treatment may be justified as a last resort option.Data are not available for public, however upon a reasonable request it may be provided.