TY - JOUR T1 - Efficacy of combined use of a stent retriever and aspiration catheter in mechanical thrombectomy for acute ischemic stroke JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 892 LP - 897 DO - 10.1136/neurintsurg-2021-017837 VL - 14 IS - 9 AU - Tomohiro Okuda AU - Koichi Arimura AU - Ryu Matsuo AU - So Tokunaga AU - Kenta Hara AU - Shinya Yamaguchi AU - Hidenori Yoshida AU - Ryota Kurogi AU - Katsuharu Kameda AU - Osamu Ito AU - Tomoyuki Tsumoto AU - Koji Iihara AU - Taichiro Mizokami AU - Takeshi Uwatoko AU - Ataru Nishimura AU - Katsuma Iwaki AU - Masahiro Mizoguchi A2 - , Y1 - 2022/09/01 UR - http://jnis.bmj.com/content/14/9/892.abstract N2 - Background The efficacy of combined stent retriever (SR) and aspiration catheter (AC; combined technique: CBT) use for acute ischemic stroke (AIS) is unclear. We investigated the safety and efficacy of single-unit CBT (SCBT)—retrieving the thrombus as a single unit with SR and AC into the guide catheter—compared with single use of either SR or contact aspiration (CA).Methods We analysed 763 consecutive patients who underwent mechanical thrombectomy for AIS between January 2013 and January 2020, at six comprehensive stroke centers. Patients were divided into SCBT and single device (SR/CA) groups. The successful recanalization with first pass (SRFP) and other procedural outcomes were compared between groups.Results Overall, 240 SCBT and 301 SR/CA (SR 128, CA 173) patients were analyzed. SRFP (modified Thrombolysis In Cerebral Infarction (mTICI) ≥2c, 43.3% vs 27.9%, p<0.001; mTICI 3, 35.8% vs 25.5%, p=0.009) and final mTICI ≥2b recanalization (89.1% vs 82.0%, p=0.020) rates were significantly higher, puncture-to-reperfusion time was shorter (median (IQR) 43 (31.5–69) vs 55 (38–82.2) min, p<0.001), and the number of passes were fewer (mean±SD 1.72±0.92 vs 1.99±1.01, p<0.001) in the SCBT group. Procedural complications were similar between the groups. In subgroup analysis, SCBT was more effective in women, cardioembolic stroke patients, and internal carotid artery and M2 occlusions.Conclusions SCBT increases the SRFP rate and shortens the puncture-to-reperfusion time without increasing procedural complications.Data are available upon reasonable request. ER -