RT Journal Article
SR Electronic
T1 Effect of the anastomosis between the posterior inferior cerebellar artery and the superior cerebellar artery on outcomes of acute basilar artery occlusion after endovascular treatment
JF Journal of NeuroInterventional Surgery
JO J NeuroIntervent Surg
FD BMJ Publishing Group Ltd.
SP jnis-2022-019409
DO 10.1136/jnis-2022-019409
A1 Jiacheng Huang
A1 Weilin Kong
A1 Jie Yang
A1 Maolin Wang
A1 Xianjun Huang
A1 Yan Wang
A1 Jun Luo
A1 Youlin Wu
A1 Guoyong Zeng
A1 Yue Wan
A1 Jiaxing Song
A1 Linyu Li
A1 Jinrong Hu
A1 Shuai Liu
A1 Weidong Luo
A1 Yan Tian
A1 Hongfei Sang
A1 Zhongming Qiu
A1 Fengli Li
A1 Wouter Schonewille
A1 Chang Liu
A1 Wenjie Zi
YR 2022
UL http://jnis.bmj.com/content/early/2022/10/03/jnis-2022-019409.abstract
AB Background The effects of secondary collateral compensation on outcomes remain unclear in patients with acute basilar artery occlusion (BAO) after endovascular treatment (EVT). This study aimed to evaluate the benefits of the anastomosis between the posterior inferior cerebellar artery (PICA) and the superior cerebellar artery (SCA) in BAO after EVT.Methods This cohort study was conducted using data from the Endovascular Treatment for Acute Basilar Artery Occlusion Study Registry. Patients with acute BAO and treated with EVT were included. The primary outcome was a modified Rankin Scale score of 0–2 at 90 days. Safety outcomes included symptomatic intracerebral hemorrhage (SICH) and 90-day mortality.Results Of the 646 patients included in the study, 196 (30.3%) patients had a PICA–SCA anastomosis. The PICA–SCA anastomosis was significantly associated with independent functional outcome at 90 days (67/196 (34.2%) vs 109/450 (24.2%), adjusted OR (aOR) 1.80 (95% CI 1.13 to 2.86), p=0.01) and was significantly associated with a decreased rate of SICH (40/442 (9.0%) vs 5/193 (2.6%), aOR 0.29 (95% CI 0.11 to 0.76), p=0.01). No significant difference was found between PICA–SCA anastomosis and 90-day mortality (219/450 (48.7%) vs 80/196 (40.8%), aOR 0.72 (95% CI 0.48 to 1.08), p=0.11). Subgroup analysis showed that the association between independent functional outcome and PICA–SCA anastomosis was strongest in patients with middle BAO (27/77 (35.1%) vs 22/118 (18.6%), aOR 2.64 (95% CI 1.13 to 6.15), p=0.03).Conclusions The PICA–SCA anastomosis is significantly associated with better functional outcomes in patients with acute BAO after EVT, especially in those with middle BAO.Data are available upon reasonable request. Data are available from the corresponding author upon reasonable requests.