TY - JOUR T1 - Correspondence on “Nickels and tines: the myth of nickel allergy in intracranial stents” by Vanent <em>et al</em> JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 1286 LP - 1287 DO - 10.1136/neurintsurg-2022-018823 VL - 14 IS - 12 AU - Anastasios Apostolos AU - Stamatios Gregoriou AU - Maria Drakopoulou AU - Georgios Trantalis AU - Georgios Tsivgoulis AU - Costas Tsioufis AU - Konstantinos Toutouzas Y1 - 2022/12/01 UR - http://jnis.bmj.com/content/14/12/1286.abstract N2 - Dear Editor,Nickel hypersensitivity remains a hot issue, as endovascular interventions and implantation of devices gain more ground. The extent and the real incidence of nickel allergy secondary to device placement remain under investigation.1 A wide variety of clinical signs and symptoms have been described, depending on the area of device implantation.1 2 A recent meta-analysis supported that adverse events were increased in nickel-allergic patients after endovascular interventions.3 Against this context, we read with great interest the article by Vanent et al on nickel allergy in intracranial stents.4 We would like to congratulate the authors for getting involved in such an interesting topic; however, we have some concerns about their study.First, an in vitro observation cannot be considered as adequate for ruling out the existence of nickel hypersensitivity syndrome after intracranial stenting. We acknowledge that in the experiment nickel release was not observed, but it was performed under … ER -