TY - JOUR T1 - Bioresorbable flow diverters for the treatment of intracranial aneurysms: review of current literature and future directions JF - Journal of NeuroInterventional Surgery JO - J NeuroIntervent Surg SP - 178 LP - 182 DO - 10.1136/neurintsurg-2022-018941 VL - 15 IS - 2 AU - Alexander A Oliver AU - Kent D Carlson AU - Cem Bilgin AU - Jorge L Arturo Larco AU - Ramanathan Kadirvel AU - Roger J Guillory II AU - Dan Dragomir Daescu AU - David F Kallmes Y1 - 2023/02/01 UR - http://jnis.bmj.com/content/15/2/178.abstract N2 - The use of flow diverters is a rapidly growing endovascular approach for the treatment of intracranial aneurysms. All FDA-approved flow diverters are composed of nitinol or cobalt-chromium, which will remain in the patient for the duration of their life. Bioresorbable flow diverters have been proposed by several independent investigators as the next generation of flow diverting devices. These devices aim to serve their transient function of occluding and healing the aneurysm prior to being safely resorbed by the body, eliminating complications associated with the permanent presence of conventional flow diverters. Theoretical advantages of bioresorbable flow diverters include (1) reduction in device-induced thrombosis; (2) reduction in chronic inflammation and device-induced stenosis; (3) reduction in side branch occlusion; (4) restoration of physiological vasomotor function; (5) reduction in imaging artifacts; and (6) use in pediatric applications. Advances made in the similar bioresorbable coronary stenting field highlight some of these advantages and demonstrate the feasibility and safety of bioresorbable endovascular devices in the clinic. The current work aims to review the progress of bioresorbable flow diverters, identify opportunities for further investigation, and ultimately stimulate the advancement of this technology. ER -