RT Journal Article SR Electronic T1 E-026 Long-term clinical outcomes of arteriovenous fistula treated with the penumbra smart coil system: a subset analysis of the prospective, multicenter smart registry JF Journal of NeuroInterventional Surgery JO J NeuroIntervent Surg FD BMJ Publishing Group Ltd. SP A91 OP A91 DO 10.1136/jnis-2023-SNIS.126 VO 15 IS Suppl 1 A1 Abdelsalam, A A1 Burks, J A1 Eatz, T A1 Ramsay, I A1 Fountain, H A1 Park, M A1 Bellon, R A1 Schirmer, C A1 Spiotta, A A1 Starke, R YR 2023 UL http://jnis.bmj.com/content/15/Suppl_1/A91.abstract AB Background Endovascular embolization techniques are generally the primary therapeutic modality for the treatment of arteriovenous fistula (AVF). This subset analysis aimed to assess the prospective long-term clinical outcomes of AVF treated with the SMART COIL System.Methods Forty-one patients from the SMART registry (a prospective, multicenter, single-arm, postmarket registry) had AVF treated with endovascular coiling and were followed up to 12 ± 6 months after the procedure.Results No patients (0/41) had a procedural device-related serious adverse event (SAE). Re-access with a guidewire due to catheter kickout was not required in 85.4% (35/41) of patients. Complete or adequate occlusion immediately after the procedure was achieved in 87.8% (36/41) of patients. The periprocedural SAE rate was 2.4% (1/41), and no periprocedural deaths occurred (0/41). Retreatment through follow-up occurred in 3.4% (1/29) of patients. At one year, the lesion occlusion was better or stable in 93.3% (28/30) of patients. The SAE rate after 24 hours through 365 days after the procedure was 26.8% (11/41). The one-year all-cause mortality rate was 2.4% (1/41), and 90.9% (20/22) of patients had a modified Rankin Scale score of 0 to 2 at one-year follow-up.Conclusion Coiling of arteriovenous fistula with the SMART COIL System was safe and effective at one year.View this table:Abstract E-026 Table 1 Clinical outcomes at (12 ± 6 months) follow-up of patients with arteriovenous fistula treated with the Penumbra SMART COIL System. Data are reported as percentage (n/N)Disclosures A. Abdelsalam: None. J. Burks: None. T. Eatz: None. I. Ramsay: None. H. Fountain: None. M. Park: None. R. Bellon: None. C. Schirmer: 1; C; Penumbra. A. Spiotta: 1; C; Penumbra. 2; C; penumbra. R. Starke: 2; C; penumbra.