PT  - JOURNAL ARTICLE
AU  - Schulze-Zachau, Victor
AU  - Brehm, Alex
AU  - Ntoulias, Nikolaos
AU  - Krug, Nadja
AU  - Tsogkas, Ioannis
AU  - Blackham, Kristine
AU  - Möhlenbruch, Markus
AU  - Jesser, Jessica
AU  - Cervo, Amedeo
AU  - Kreiser, Kornelia
AU  - Althaus, Katharina
AU  - Maslias, Errikos
AU  - Michel, Patrik
AU  - Saliou, Guillaume
AU  - Riegler, Christoph
AU  - Nolte, Christian
AU  - Maier, Ilko
AU  - Jamous, Ala
AU  - Rautio, Riitta
AU  - Ylikotila, Pauli
AU  - Fargen, Kyle
AU  - Wolfe, Stacey
AU  - Castellano, Davide
AU  - Boghi, Andrea
AU  - Kaiser, Daniel
AU  - Cuberi, Ani
AU  - Kirschke, Jan
AU  - Schwarting, Julian
AU  - Limbucci, Nicola
AU  - Renieri, Leonardo
AU  - Kasab, Sami Al
AU  - Spiotta, Alejandro
AU  - Fragata, Isabel
AU  - Rodríguez-Ares, Tania
AU  - Maurer, Christoph
AU  - Ansgar, Berlis
AU  - Moreu, Manuel
AU  - López-Jurado, Alfonso López-Frías
AU  - Pérez-García, Carlos
AU  - Commodaro, Christian
AU  - Pileggi, Marco
AU  - Mascitelli, Justin
AU  - Giordano, Flavio
AU  - Casagrande, Walter
AU  - Purves, Cynthia
AU  - Bester, Maxim
AU  - Flottmann, Fabian
AU  - Kan, Peter
AU  - Edhayan, Gautam
AU  - Hofmeister, Jeremy
AU  - Machi, Paolo
AU  - Kaschner, Marius
AU  - Weiss, Daniel
AU  - Katan, Mira
AU  - Fischer, Urs
AU  - Psychogios, Marios
TI  - P137/17  Incidence and outcome of perforations occuring during Medium-Vessel Occlusion thrombectomy compared to Large-Vessel occlusion thrombectomy
AID  - 10.1136/jnis-2023-ESMINT.165
DP  - 2023 Sep 01
TA  - Journal of NeuroInterventional Surgery
PG  - A67--A67
VI  - 15
IP  - Suppl 2
4099  - http://jnis.bmj.com/content/15/Suppl_2/A67.1.short
4100  - http://jnis.bmj.com/content/15/Suppl_2/A67.1.full
SO  - J NeuroIntervent Surg2023 Sep 01; 15
AB  - Introduction Vessel perforation during thrombectomy is a severe complication and is hypothesized to be more frequent during MeVO compared to LVO thrombectomy.Aim of the study To compare the incidence and outcome of patients with perforation during MeVO and LVO thrombectomy and to report on the procedural steps that led to perforation.Methods In this multicenter retrospective cohort study, data of consecutive patients with vessel perforation during thrombectomy between January 01, 2015 and September 30, 2022 were collected. The primary outcomes were independent functional outcome (i.e. modified Rankin Scale 0–2) and all-cause mortality at 90 days. Binomial test, chi-squared test and t-test for unpaired samples were used for statistical analysis.Results During 25,769 thrombectomies (5,124 MeVO, 20,645 LVO) in 25 stroke centers, perforation occurred in 335 patients (1.3%; mean age 72 years, 62% female). Perforation occurred more often in MeVO thrombectomy (2.4%) than in LVO thrombectomy (1.0%, p < 0.001). More MeVO than LVO patients with perforation achieved functional independence at three months (25.7% vs 10.9%; p=0.001). All-cause mortality did not differ (overall 51.6%). Navigation beyond the occlusion and retraction of stent-retriever/aspiration catheter were the two most common procedural steps that led to perforation.Conclusions In our cohort, perforation was approximately twice as frequent in MeVO than in LVO thrombectomy. Considering the rather benign natural course of MeVO stroke, physicians should be avoiding perforation during MeVO thrombectomy by all means. Efforts to optimize the procedure may focus on navigation beyond the occlusion site and retraction of stent-retriever/aspiration catheter.Disclosure of Interest Nothing to disclose