Effects of rtPA on revascularization, clinical outcome and ICH
| Outcome | Penumbra (N=41) | Intravenous & intra-arterial rtPA + Penumbra (N=36) | Intravenous rtPA + Penumbra (N=29) | Intra-arterial rtPA + Penumbra (N=51) |
| TIMI 2–3, % | 90.2 | 88.9 | 75.9% | 90.2 |
| Asymptomatic ICH, % | 19.5 | 13.9 | 17.2 | 5.9 |
| Symptomatic ICH, % | 4.9 | 5.6 | 0 | 9.8 |
| Death at 90 days, % | 19.5 | 22.2 | 24.1 | 17.6 |
| mRS ≤2 at 90 days, %* | 43.8 | 43.3 | 32.0 | 42.9 |
↵* Deaths were rated as 6 on the mRS score.
ICH, intracerebral hemorrhage, mRS, modified Rankin Scale; TIMI, thrombolysis in myocardial infarction.