Initial clot | AOL* | Time† (min) | Residual location | TICI‡ | FER | HT‡‡ | Imaging | NIHSS improvement¶ | mRS¶ | Reason for termination | Additional data |
Successful proximal recanalization | |||||||||||
ICA-L | 2 | 405 | Distal M1 | IIa | Y | 5 h MRA | 13 | 1 | Max dose | Adjuvant IA Reopro | |
ICA-L | 3 | 355 | Distal M1 | IIb | Y | HI2 | 5 h MRA | −18 | 6 | Futile | |
ICA-T | 2 | 570 | Mid-M1 | IIa | P | PH2§ | 5 h MRA | 9 | 5 | Futile | Aspirin |
Tandem | 2 | 147 | Proximal M1 | 0 | Y | 5 h MRA | 2 | 4 | Technical difficulties | Distal clot at ICA terminus; heparin | |
Tandem | 3 | 506 | Proximal M1 | I** | P | HI1 | 5 h MRA | 8 | 5 | Technical difficulties | CAS only; pressors |
Tandem | 2 | 360 | Distal M1 | IIb | Y | HI1 | 24 h CTA | 15 | 1 | Max dose | IA tPA only; heparin |
Tandem | 3 | 315 | Mid-M1 | IIb** | Y | PH1§ | 5 h MRA | 12 | 1 | Good flow | CAS only; aspirin |
ICA-L†† | 3 | 450 | Distal M1 | IIb | N | HI2 | 5 h MRA | 19 | 4 | UTA (2 pulls) | Failed IV tPA |
ICA-L | 2 | 190 | Distal M1 | IIa | N | 5 h MRA | −23 | 6 | UTA (3 pulls) | ||
ICA-L†† | 3 | 534 | Distal M1 | I | N | HI2 | 5 h MRA | −17 | 6 | Technical difficulties | CAS+Merci; aspirin |
ICA-L†† | 2 | 585 | Proximal M1 | IIa | N | HI1 | 16 h MRA | −4 | 4 | Complication | CAS+Merci; aspirin; pressors |
ICA-L | 3 | 290 | Distal M1 | 0 | N | PH2§ | 9 h MRA | 12 | 4 | Complication | |
Failed proximal recanalization | |||||||||||
ICA-T | 0 | 330 | Same | N | 24 h CTA | −3 | 6 | ||||
ICA-T | 0 | 430 | Same | N | 24 h MRA | −23 | 6 | Aspirin | |||
ICA-T | 1 | 265 | Same | N | HI1 | 5 h MRA | 9 | 6 | Pressors | ||
Tandem | 0 | 250 | Same | N | UTA | 24 h TCD | −19 | 5 | |||
ICA-T | 1 | 380 | Same | N | 5 h MRA | −21 | 6 |
↵* Recanalization score of proximal ICA aspect of clot.
↵† Time from symptom onset to intervention.
↵‡ Reperfusion of residual MCA clot.
↵§ Symptomatic HT.
↵¶ At time of discharge. Negative NIHSS numbers reflect a neurological worsening at the time of discharge.
↵** Spontaneous recanalization of the MCA seen after CAS.
↵†† The entire extracranial and intracranial ICA to the terminus was occluded in three patients.
↵‡‡ HI1, HI2, PH1, PH2=types of HT classified according to the European Cooperative Acute Stroke Study (ECASS) definition.9
AOL, arterial occlusive lesion; CAS, carotid angioplasty and stenting; CTA, computed tomographic angiography; FER, facilitated endogenous recanalization at 24 h; HT, hemorrhagic transformation; IA, intra-arterial; ICA-T and ICA-L, contiguous intracranial internal carotid–middle cerebral artery; IV, intravenous; M1, horizontal segment of the middle cerebral artery; MRA, magnetic resonance angiography; mRS, modified Rankin score; NIHSS, National Institutes of Health Stroke Scale; P, partial FER; Tandem, tandem extracranial internal carotid–middle cerebral artery; TCD, transcranial Doppler ultrasonography; TICI, Thrombolysis in Cerebral Ischemia23; tPA, tissue plasminogen activator; UTA, unable to assess.