Study | No of patients | Antiplatelet regimen | Intraoperative rupture (n (%)) | Intracerebral hemorrhage (n (%)) | Thromboembolic event | Stroke | EVD related complications | Outcome |
Jankowitz13 | 41 | Intraoperative glycoprotein IIbIIIa antagonist followed by postoperative aspirin and clopidogrel. Standard use of heparin during procedure was maintained | 3 (4.5) | 2 (5) |
| 5 with good outcome |
| Described as good, but no clear specification was provided |
Thantinen14 | 61 | No standard antiplatelet regimen. Some received intraoperative acetylsalicylate and some received intraoperative heparin followed by aspirin and clopidogrel | 4 (7) | Total events=7 (11%) | Not described | Not described |
| |
Lodi (current study) | 22 | Loading dose of 300 mg clopidogrel and aspirin at least 2 h prior to stent placement followed by 75 mg of clopidogrel and 325 mg aspirin daily for 4 weeks. All patients received intravenous heparin to obtain an activated coagulation time of 1.5–2 times baseline prior to stent deployment. | 0 | 0 |
| 0 | 0 |
|
EVD, extraventricular drainage; GOS, Glasgow Outcome Scale.