Comparison of treatment and outcomes between the two study groups: those treated ≤6 h versus those treated >6 h from symptom onset
Endpoints | Time to treatment | p Value | |
≤6 h (N=26) | >6 h (N=27) | ||
Mean age (years) | 65 | 65 | 0.968 |
Race | |||
African American | 8 (30.8) | 12 (44.4) | 0.385 |
Caucasian American | 17 (65.4) | 15 (55.6) | |
Hispanic American | 1 (3.8) | 0 | |
Gender, M/F (%) | 12/14 (46.2/53.8) | 14/13 (51.9/48.1) | 0.786 |
Median time to treatment (h) | 4.0 | 8.5 | <0.0001 |
90-day mRS ≤2 | 10 (38.5) | 11 (40.7) | 1.0 |
90-day mRS ≤3 | 15 (57.7) | 14 (51.9) | 0.785 |
Mortality | 4 (15.4) | 8 (29.6) | 0.327 |
Intravenous tPA | 13 (50.0) | 5 (18.5) | 0.021 |
Recanalization | |||
Complete | 16 (61.5) | 16 (59.3) | 0.362 |
Partial | 10 (38.5) | 9 (33.3) | |
None | 0 | 2 (7.4) | |
Mean NIHSS | 19.1 | 15.3 | 0.025 |
Location of occlusion | |||
Internal carotid artery | 6 (23.1) | 6 (22.2) | 0.955 |
Middle cerebral artery | 16 (61.5) | 16 (59.3) | |
Posterior circulation | 4 (15.4) | 5 (18.5) | |
Intracranial hemorrhage | 3 (11.5) | 5 (18.5) | 0.704 |
mRS, modified Rankin Score; NIHSS, National Institute of Health Stroke Scale Score; tPA, tissue plasminogen activator.