Comparison of clinical outcome measures to rapid neurological improvement
| Outcome measure | RNI (n=35) | No RNI (n=77) | p Value |
| Change in NIHSSS | |||
| 0–24 h | 10 (7–11) | 0 (−2–4) | <0.0001* |
| Presentation–discharge | 11 (8–13) | 2 (−4–6.5) | <0.0001* |
| 24 h—discharge | 1 (0–2) | 1 (0–3) | 0.689* |
| mRS ≤2 at 3 months | 33 (94.1%) | 22 (28.6%) | <0.0001† |
25–75% quartiles (in parentheses) for continuous data; percentages (in parentheses) for nominal/ordinal data.
NIHSSS was treated as non-parametric continuous data.
↵* Wilcoxon rank sums two sample test.
↵† Pearson χ2; Bonferroni correction for multiple tests requires p<0.0125 for significance.
mRS, modified Rankin Scale; NIHSSS, National Institutes of Health stroke scale score; RNI, rapid neurological improvement.