Baseline characteristics of hypothermia patients
| Demographics | |
| Age, mean (SD) | 59.7 (14.6) |
| Men, n (%) | 12 (60%) |
| Hypertension, n (%) | 16 (80%) |
| Diabetes, n (%) | 5 (25%) |
| Atrial fibrillation, n (%) | 6 (30%) |
| Neurological severity | |
| Pre-NIHSS, mean (SD) | 19 (16–22) |
| ASPECTS, median (IQR) | 6 (6–7) |
| Treatment | |
| Intravenous tPA given, n (%) | 10 (50%) |
| Symptom onset to groin puncture (min), median (IQR) | 309 (245–400) |
| Symptom onset to cooling initiation (min), median (IQR) | 432 (325–534) |
| Cooling initiation to hypothermia (min), mean (SD)* | 64 (50) |
| Duration of cooling (h), mean (SD)* | 12.1 (2.7) |
| Duration of rewarming (h), mean (SD) | 11.5 (4.8) |
| Radiographic imaging | |
| Post-procedural infarct volume cm3, median (IQR) | 78 (16–107) |
| Asymptomatic hemorrhage (HI1/HI2), n (%) | 2 (10%) |
| Symptomatic hemorrhage (PH1/2), n (%) | 1 (5%) |
| HARM status on 36–72 h MRI, n (%)† | 3 (21%) |
| Complications | |
| Pneumonia, n (%) | 5 (25%) |
| Bacteremia, n (%) | 1 (5%) |
| Deep vein thrombosis, n (%) | 1 (5%) |
| Urinary tract infection, n (%) | 4 (20%) |
| Disposition status | |
| NIHSS on discharge, median (SD)‡ | 10 (3–15) |
| mRS on discharge, median (SD) | 4 (3–6) |
| 90-day outcomes | |
| Good outcome (mRS 0–2), n (%) | 6 (30%) |
| Acceptable outcome (mRS 0–3), n (%) | 9 (45%) |
*Two patients did not achieve the target temperature.
†MRI was not obtained from six patients.
‡Expired patients were not included in the discharge NIHSS calculation.
ASPECTS, Alberta Stroke Program Early CT Score; HARM, hyperintense acute reperfusion marker; mRS, modified Rankin Score; NIHSS, NIH Stroke Scale.