Table 2

Comparison in treatment and outcomes between patients treated ≤8 h and those treated >8 h from symptom onset

EndpointsTime to treatmentp Value
≤8 h (N=173)>8 h (N=74)
Mean age (years)67640.054 (NS)
Gender (M/F)78/95 (45.1/54.9)38/36 (51.4/48.6)0.405 (NS)
Mean time to treatment (h)4.816.4<0.0001
90-day mRS≤2 (%)74 (42.8)31 (41.9)1.0 (NS)
90-day mRS≤3 (%)95 (54.9)41 (55.4)1.0 (NS)
Mortality (%)43 (24.9)15 (20.3)0.513 (NS)
Intravenous tPA (%)95 (55.2)20 (27.0)<0.0001
Recanalization
 Complete (TICI 2B or 3) (%)124 (71.7)60 (81.1)0.151 (NS)
 None (%)49 (28.3)14 (18.9)
 Mean NIHSS18.717.20.069 (NS)
Location of occlusion
 Anterior circulation (MCA or ICA)158 (92.4)61 (83.6)0.062 (NS)
 Isolated MCA occlusion119 (69.6)49 (67.1)0.763 (NS)
 Intracranial hemorrhage34 (19.7)14 (18.9)1.0 (NS)
 Symptomatic hemorrhage15 (8.7)5 (6.8)0.80 (NS)
  • ICA, internal carotid artery; MCA, middle cerebral artery; mRS, modified Rankin Score; NIHSS, National Institutes of Health Stroke Scale; TICI, thrombolysis in cerebral infarction; tPA, tissue plasminogen activator.