Baseline clinical variables, treatment modalities and univariate analysis for predictors of good outcome (mRS ≤2) at 90 days
| Variable | N (%) | Median (IQR) | mRS ≤2* | ||
|---|---|---|---|---|---|
| OR | p Value | 95% CI | |||
| Age (years) | 66 (29–93) | 0.97 | 0.041 | 0.94 to 0.99 | |
| NIHSS score | 17 (4–36) | 0.78 | 0.000 | 0.70 to 0.88 | |
| Baseline ASPECT score | 9 (4–10) | 1.50 | 0.008 | 1.11 to 2.04 | |
| Time to procedure (h)* | 4.45 (1.16–34.3) | 0.99 | 0.113 | 0.99 to 1.00 | |
| Treatment time (min)† | 70 (15–289) | 0.99 | 0.047 | 0.980 to 0.99 | |
| Men | 61 (54.4) | 1.63 | 0.215 | 0.75 to 3.5 | |
| Left MCA | 54 (54) | 0.79 | 0.056 | 0.34 to 1.79 | |
| HTN | 81 (72.3) | 0.88 | 0.766 | 0.37 to 2.04 | |
| DM | 22 (19.8) | 0.43 | 0.124 | 0.153 to 1.252 | |
| Afib | 40 (36) | 0.88 | 0.77 | 0.39 to 1.88 | |
| Smoking | 16 (17) | 1.41 | 0.53 | 0.46 to 4.32 | |
| CAD | 29 (26.8) | 1 | 1 | 0.47 to 2.47 | |
| TICI ≥2b | 97 (86.6) | 2.07 | 0.010 | 1.18 to 3.62 | |
| Intubation | 13 (12.4) | 0.45 | 0.2 | 0.13 to 1.59 | |
| Intravenous tPA | 46 (41) | 1.6 | 0.20 | 0.75 to 3.63 | |
| M1 | 70 (62) | 1.2 | 0.53 | 0.57 to 2.89 | |
| M2 | 9 (8) | 1.18 | 0.8 | 0.27 to 5.00 | |
| ICA terminus | 21 (18.7) | 0.81 | 0.69 | 0.29 to 2.23 | |
| Tandem | 21 (18.7) | 2.08 | 0.16 | 0.73 to 5.88 | |
| Any ICA | 38 (33.9) | ||||
| Basilar | 12 (10.7) | ||||
| Number of passes | 2 (1–8) | 0.88 | 0.35 | 0.68 to 1.14 | |
| Intra-arterial tPA | 3 (2.6) | ||||
| Stent retriever | 32 (28.5) | ||||
| Merci | 6 (5.3) | ||||
| Intra-arterial tPA | 3 (2.6) | ||||
| Multiple devices | 5 (4.4) | ||||
| Hemorrhagic transformation | 31 (27) | ||||
| Parenchymal hematoma | 11 (9.8) | ||||
| Symptomatic bleed | 7 (6.2) | ||||
| ENT | 4 (3.5) | ||||
| mRS ≤2 at 90 days | 52 (46.1) | ||||
| mRS 6 | 35 (31) | ||||
| Pure MAT | 66 (59) | 1.14 | 0.73 | 0.522 to 2.50 | |
| Aspiration catheter 0.4/0.5/0.6 | 0.75 | 0.45 | 0.36 to 1.55 | ||
| Aspiration catheter brand | Navien (84) | 1.2 | 0.46 | 0.73 to 1.97 | |
| DAC (4) | |||||
| Penumbra (23) | |||||
*Time to procedure: from onset of symptoms or last seen normal to groin puncture.
†Treatment time: from puncture to recanalization.
ASPECT, Alberta Stroke Program Early CT score; CAD, coronary artery disease; DM, diabetes mellitus; ENT, embolization to a new territory; HTN, hypertension; IA, intra-arterial; ICA, internal carotid artery; MAT, manual aspiration thrombectomy; MCA, middle cerebral artery; mRS, modified Rankin Scale; NIHSS, NIH Stroke Scale; TICI, Thrombolysis in Cerebral Infarction.