Univariate (n=147) | Multivariate (n=143) | ||||||
---|---|---|---|---|---|---|---|
OR | 95% CI | p Value | Included in model? | OR | 95% CI | p Value | |
Age | 0.98 | 0.96 to 0.999 | 0.04 | Yes | 0.98 | 0.95 to 1.01 | 0.14 |
Female | 1.15 | 0.59 to 2.23 | 0.68 | No | |||
Time from symptom onset to CT (h) | 0.996 | 0.96 to 1.04 | 0.83 | Yes* | 0.99 | 0.92 to 1.03 | 0.50 |
Time from CT to groin puncture (procedure start) (h) | 0.82 | 0.59 to 1.14 | 0.24 | Yes* | 0.66 | 0.40 to 1.02 | 0.08 |
IV tPA | 0.72 | 0.36 to 1.41 | 0.33 | Yes* | 0.67 | 0.27 to 1.64 | 0.38 |
IA tPA | 1.11 | 0.51 to 2.43 | 0.79 | Yes* | 1.05 | 0.40 to 2.80 | 0.92 |
Device: Penumbra | 0.53 | 0.24 to 1.13 | 0.10 | No | |||
Device: Solitaire | 1.85 | 0.78 to 4.41 | 0.16 | No | |||
Device: Other | 1.59 | 0.44 to 5.74 | 0.48 | No | |||
Recanalization time (min) | 0.99 | 0.98 to 0.995 | 0.002 | Yes | 0.99 | 0.97 to 0.997 | 0.02 |
Recanalization time (10 min unit) | Yes | 0.87 | 0.77 to 0.97 | ||||
AFIB | 1.15 | 0.57 to 2.31 | 0.70 | Yes* | 1.27 | 0.46 to 3.57 | 0.65 |
Diabetes | 0.32 | 0.13 to 0.75 | 0.009 | Yes | 0.27 | 0.08 to 0.79 | 0.02 |
Hypertension | 0.59 | 0.28 to 1.22 | 0.15 | Yes* | 0.77 | 0.29 to 2.03 | 0.59 |
Sedation: GA | 0.34 | 0.096 to 1.23 | 0.10 | Yes* | 1.14 | 0.22 to 5.48 | 0.87 |
Baseline NIHSS | 0.92 | 0.87 to 0.98 | 0.01 | Yes | 0.88 | 0.81 to 0.95 | 0.002 |
Post TICI Flow: ‘Good’ (2b or 3) | 3.2 | 1.22 to 8.41 | 0.02 | Yes | 3.45 | 1.12 to 12.13 | 0.04 |
Hemorrhage | 0.35 | 0.13 to 0.93 | 0.04 | Yes | 0.27 | 0.08 to 0.79 | 0.03 |
Procedural complications | 0.28 | 0.06 to 1.34 | 0.11 | Yes* | 0.20 | 0.02 to 1.13 | 0.09 |
Variables achieving statistical significance are highlighted in bold type.
*Although not a statistically significant variable on univariate analysis, it was included due to clinical significance.
AFIB, atrial fibrillation; GA, general anesthetic; IA, intra-arterial; IV tPA, intravenous tissue plasminogen activator; NIHSS, National Institutes of Health Stroke Scale; TICI, Thrombolysis in Cerebral Ischemia.