Patient characteristics according to age group
| Treatment group | ||||
|---|---|---|---|---|
| Group 1 (n=68) | Group 2 (n=74) | Group 3 (n=72) | p Value | |
| Women (%) | 39.7 | 47.9 | 72.2 | <0.01 |
| Age | 59±9 | 75±3 | 83±3 | <0.01 |
| Diabetes (%) | 10.6 | 21.4 | 24.6 | 0.09 |
| Hypertension (%) | 47 | 77.1 | 81.2 | <0.01 |
| Atrial fibrillation (%) | 30.8 | 41.4 | 60 | <0.01 |
| Dyslipidemia (%) | 36.4 | 48.6 | 38.8 | 0.31 |
| Glycemia | 143±52 | 137±51 | 127±47 | 0.70 |
| Systolic BP | 132±28 | 154±32 | 151±27 | <0.01 |
| Diastolic BP | 76±14 | 83±17 | 86±21 | 0.229 |
| Intravenous tPA (%) | 60 | 63.4 | 50.7 | 0.30 |
| Terminal ICA occlusion (%) | 41.5 | 37.3 | 32.8 | 0.59 |
| Baseline NIHSS (IQR) | 19 (7) | 19 (6) | 19 (3) | 0.92 |
| Median ASPECTS (IQR) | 10 (0) | 10 (1) | 10 (1) | 0.87 |
| Symptomatic ICH (%) | 7.7 | 7.1 | 10.6 | 0.74 |
| Time to groin puncture (min) | 172±96 | 159±104 | 188±84 | 0.146 |
| Time to recanalization (min) | 304±93 | 312±116 | 329±102 | 0.26 |
| Recanalization (≥TICI 2b, %) | 60.6 | 50.7 | 49.3 | 0.36 |
| Infarct volume (mL) | 96±131 | 109±139 | 87±116 | 0.71 |
| mRS (≤2 at 3 months, %) | 45.8 | 33.5 | 27.3 | 0.11 |
ASPECTS, Alberta Stroke Program Early CT score; BP, blood pressure; ICA, internal carotid artery; ICH, intracranial hemorrhage; mRS, modified Rankin Scale; NIHSS, NIH Stroke Scale; TICI, Thrombolysis In Cerebral Infarction; tPA, tissue plasminogen activator.