Table 1

Variability in reporting stroke intervention time intervals

StudyOnset to groinStroke onset to enrollmentTime from stroke onset to start of treatment*Time to presentation†Presentation to treatment‡Onset to IA therapyOnset to allocationMean procedure duration§Baseline angiogram to >/=TICI2b (min)¶Stroke onset to procedure termination (min)Door to arteriography
MELT199±65 min
MERCI4.3±1.7 h2.1±1.0 h
Multi-MERCI4.3 (3.2 to 5.3) h1.6 (1.2–2.3) h
Penumbra4.3±1.5 h1.9±1.6 h
SOLITARE169 (45–630) min147 (40–450) min37 (4–236) min
IMS 1 and 2208–395 min
SYNTHESIS Expansion3:45 (1:14–4:20) h
IMS 3208±46 min249±50.6 min
MR RESCUE5.3±1.6 h
  • *Stroke onset to the beginning of intra-arterial pharmacologic or mechanical thrombolysis.

  • †Probably mean onset to door.

  • ‡Presentation to first angiographic run.

  • §Not defined (groin puncture to close?).

  • ¶Mean time needed for recanalization of the target artery, calculated from the baseline angiogram.

  • IA, intra-arterial; IMS, Interventional Management of Stroke; MELT, Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial; MERCI, Mechanical Embolus Removal in Cerebral Ischemia; MR RESCUE, Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy; SYNTHESIS Expansion, Intra-arterial versus Systemic Thrombolysis for Acute Ischemic Stroke; SWIFT, Solitaire with the Intention for Thrombectomy; TICI, Thrombolysis in Cerebral Ischemia.