Variability in reporting stroke intervention time intervals
| Study | Onset to groin | Stroke onset to enrollment | Time from stroke onset to start of treatment* | Time to presentation† | Presentation to treatment‡ | Onset to IA therapy | Onset to allocation | Mean procedure duration§ | Baseline angiogram to >/=TICI2b (min)¶ | Stroke onset to procedure termination (min) | Door to arteriography |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MELT | 199±65 min | ||||||||||
| MERCI | 4.3±1.7 h | 2.1±1.0 h | |||||||||
| Multi-MERCI | 4.3 (3.2 to 5.3) h | 1.6 (1.2–2.3) h | |||||||||
| Penumbra | 4.3±1.5 h | 1.9±1.6 h | |||||||||
| SOLITARE | 169 (45–630) min | 147 (40–450) min | 37 (4–236) min | ||||||||
| IMS 1 and 2 | 208–395 min | ||||||||||
| SYNTHESIS Expansion | 3:45 (1:14–4:20) h | ||||||||||
| IMS 3 | 208±46 min | 249±50.6 min | |||||||||
| MR RESCUE | 5.3±1.6 h |
*Stroke onset to the beginning of intra-arterial pharmacologic or mechanical thrombolysis.
†Probably mean onset to door.
‡Presentation to first angiographic run.
§Not defined (groin puncture to close?).
¶Mean time needed for recanalization of the target artery, calculated from the baseline angiogram.
IA, intra-arterial; IMS, Interventional Management of Stroke; MELT, Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial; MERCI, Mechanical Embolus Removal in Cerebral Ischemia; MR RESCUE, Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy; SYNTHESIS Expansion, Intra-arterial versus Systemic Thrombolysis for Acute Ischemic Stroke; SWIFT, Solitaire with the Intention for Thrombectomy; TICI, Thrombolysis in Cerebral Ischemia.