Patient characteristics
N | Total cohort (n=159) | ‘Early recan’ time ≤60 min (n=59) | ‘Delayed recan’ time >60 min (n=100) | p Value | |
---|---|---|---|---|---|
Comorbidities (n (%)) | |||||
AFIB | 159 | 50 (31.5) | 30 (50.9) | 20 (20.0) | <0.0001 |
Diabetes | 159 | 44 (27.7) | 14 (23.7) | 30 (30.0) | 0.393 |
Hypertension | 159 | 117 (73.6) | 44 (74.6) | 73 (73.0) | 0.828 |
Preprocedure | |||||
Age (years) | 159 | 66.4 (15.2) | 68.5 (16.8) | 65.2 (14.2) | 0.197 |
Female (n (%)) | 159 | 85 (53.5) | 37 (62.7) | 48 (48.0) | 0.072 |
Baseline NIHSS | 159 | 15.9 (5.9) | 16.8 (6.1) | 15.4 (5.8) | 0.149 |
Time from onset to procedure (h) | 157 | 9.2 (8.3) | 8.0 (5.6) | 9.9 (9.6) | 0.128 |
Time from CT to groin stick (h) | 156 | 1.7 (1.1) | 1.4 (0.7) | 1.8 (1.3) | 0.019 |
IV tPA (n (%)) | 158 | 64 (40.5) | 24 (41.4) | 40 (40.0) | 0.865 |
Procedure | |||||
Sedation (n (%)) | 159 | 0.332 | |||
GA (n (%)) | 148 (93.1) | 53 (89.8) | 95 (95.0) | ||
MOD (n (%)) | 11 (6.9) | 6 (10.2) | 5 (5.0) | ||
IA tPA (n (%)) | 158 | 121 (76.6) | 43 (74.1) | 78 (78.0) | 0.581 |
Device cost (US$) | 159 | 11 892.28 (6283.23) | 10 311.58 (3821.08) | 12 824.89 (7217.02) | 0.005 |
Time to recanalization (min) | 159 | 79.0 (40.0) | 40.7 (13.6) | 101.7 (32.5) | <0.0001 |
Final TICI flow (n (%)) | 159 | 0.002 | |||
0 | 10 (6.3) | 3 (5.1) | 7 (7.0) | ||
1 | 4 (2.5) | 0 (0.0) | 4 (4.0) | ||
2A | 20 (12.6) | 3 (5.1) | 17 (17.0) | ||
2B | 75 (47.2) | 24 (40.7) | 51 (51.0) | ||
3 | 50 (31.5) | 29 (49.2) | 21 (21.0) | ||
Final TICI flow (n (%)) | 159 | 0.009 | |||
0–2A | 34 (21.4) | 6 (10.2) | 28 (28.0) | ||
2B–3 | 125 (78.6) | 53 (89.8) | 72 (72.0) | ||
Complications (n (%)) | 159 | 13 (8.2) | 2 (3.4) | 11 (11.0) | 0.05 |
Hemorrhage (n (%)) | 159 | 31 (19.5) | 9 (15.3) | 22 (22.0) | 0.30 |
Subtype (n (%)) | |||||
Hematoma | 159 | 17 (10.7) | 3 (5.1) | 14 (14.0) | 0.111 |
IVH | 159 | 3 (1.9) | 1 (1.7) | 2 (2.0) | 0.99 |
Petechial | 159 | 9 (5.7) | 3 (5.1) | 6 (6.0) | 0.99 |
SAH | 159 | 7 (4.4) | 2 (3.4) | 5 (5.0) | 0.99 |
Outcome (90 day) | |||||
mRS dichotomized (n (%)) | 147 | 0.009 | |||
mRS 0–2 | 58 (39.5) | 30 (53.6) | 28 (30.8) | ||
mRS >2 | 89 (60.5) | 26 (46.4) | 63 (69.2) |
Values are n (%) or mean (SD).
χ2 test (Fisher's exact for small cell sizes) or Student's t test for the entire patient cohort.
Additionally, we dichotomized the cohort into patients in which recanalization times were achieved in ≤60 min (‘Early recan’) and those in which recanalization times extended beyond 60 min (‘Delayed recan’).
AFIB, atrial fibrillation; GA, general anesthetic; IA, intra-arterial; IV tPA, intravenous tissue plasminogen activator; IVH, intraventricular hemorrhage; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SAH, subarachnoid hemorrhage; TICI, Thrombolysis in Cerebral Ischemia.