Characteristics of all transferred patients with anterior circulation infarcts treated with intra-arterial therapy
| Characteristic | 90 day outcome | ||
|---|---|---|---|
| Good (mRS 0–2) (n=33) | Poor (mRS 3–6) (n=73) | p Value | |
| Demographics | |||
| Age (mean (SD)) | 59.0 (12.4) | 69.4 (13.0) | <0.001 |
| Male sex (n (%)) | 21 (64) | 39 (53) | 0.326 |
| Hypertension (n (%)) | 25 (76) | 47 (64) | 0.245 |
| Atrial fibrillation (n (%)) | 11 (33) | 26 (36) | 0.819 |
| Laboratory values | |||
| HgbA1c (mean (SD)) | 5.9 (1.2) | 6.3 (1.3) | 0.150 |
| LDL (mean (SD)) | 87.6 (31.7) | 91.2 (39.2) | 0.648 |
| Neurological assessment | |||
| Pretreatment NIHSS (median (IQR)) | 17 (12–20) | 20 (17–24) | <0.001 |
| Imaging parameters | |||
| Pretreatment ASPECTS (median (IQR)) | 8 (7–9) | 7 (6–8) | <0.001 |
| Successful reperfusion, TICI ≥2b (n (%)) | 32 (97) | 51 (70) | 0.002 |
| Postprocedure infarct volume (cm3) (median (IQR)) | 21 (10–38) | 91 (31–135) | <0.001 |
| OSH CT to pretreatment CSC CT | |||
| Rate of ASPECTS decline (Δscore/h) (mean (SD)) | 0.14 (0.23) | 0.49 (0.39) | <0.001 |
| Relative rate of ASPECTS decline (ΔASPECTS/ASPECTS)/h (mean (SD)) | 0.018 (0.03) | 0.079 (0.075) | <0.001 |
| Treatment times (min) | |||
| LKN to groin puncture (median (IQR)) | 305 (255–421) | 308 (255–418) | 0.926 |
| Procedure time (median (IQR)) | 67 (44–100) | 77 (51–109) | 0.260 |
| Complications | |||
| Symptomatic hemorrhage PH1/2 (n (%)) | 1 (3) | 12 (16) | 0.051 |
ASPECTS, Alberta Stroke Program Early CT Score; CSC, comprehensive stroke center; LDL, low density lipoprotein; LKN, last known normal; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; OSH, outside hospital; PH, parenchymal hematoma; TICI, Thrombolysis in Cerebral Infarction.