Risk factors and thromboembolic complications up to 4 weeks after PED placement
| All patients (n=74) | Symptomatic strokes (%) | p Value* | OR† (95% CI) | DWI changes‡ (%) | p Value | OR (95% CI) |
|---|---|---|---|---|---|---|
| Age | 1.00 | 0.69 (0.11 to 4.37) | 1.00 | 0.94 (0.33 to 2.69) | ||
| <60 (n=38) | 3 (7.9%) | 17 (51.5%) | ||||
| >60 (n=36) | 2 (5.6%) | 12 (50.0%) | ||||
| Gender | 1.00 | 0.76 (0.08 to 7.45) | 0.03 | 9.33 (1.07 to 81.77) | ||
| Men (n=12) | 1 (8.3%) | 1 (12.5%) | ||||
| Women (n=62) | 4 (6.5%) | 28 (57.1%) | ||||
| Smoking | 1.00 | 1.21 (0.13 to 11.59) | 0.21 | 2.50 (0.66 to 9.51) | ||
| Yes (n=17) | 1 (5.9%) | 4 (33.3%) | ||||
| No (n=57) | 4 (7.0%) | 25 (55.5%) | ||||
| PRU | 0.06 | 11.32 (0.06 to 212.57) | 0.79 | 0.80 (0.28 to 2.28) | ||
| <208 (n=35) | 0 (0%) | 14 (53.8%) | ||||
| >208 (n=39) | 5 (12.8%) | 15 (48.4%) | ||||
| ARU | 1.00 | 0.59 (0.03 to 11.52) | 0.25 | 0.34 (0.06 to 1.93) | ||
| <550 (n=66) | 5 (7.8%) | 27 (54.0%) | ||||
| >550 (n=9) | 0 (0%) | 2 (45.5%) | ||||
| Procedure time (min) | <0.01 | 35.67 (1.87 to 679.58) | 1.00 | 0.98 (0.36 to 2.63) | ||
| <116 (n=53) | 0 (0%) | 18 (42.9%) | ||||
| >116 (n=21) | 5 (23.8%) | 11 (42.3%) | ||||
| Location | 0.29 | 2.62 (0.40 to 17.21) | 0.55 | 0.65 (0.19 to 2.20) | ||
| Anterior circulation (n=58) | 3 (5.2%) | 23 (53.5%) | ||||
| Posterior circulation (n=16) | 2 (12.5%) | 6 (42.9%) | ||||
| Aneurysm size | 0.06 | 7.50 (0.79 to 70.92) | 0.59 | 0.70 (0.24 to 2.05) | ||
| <1 cm(n=46) | 1 (2.2%) | 19 (54.3%) | ||||
| >1 cm(n=28) | 4 (14.3%) | 10 (45.5%) | ||||
| No of PEDs | <0.01 | 28.48 (1.50 to 539.88) | 0.36 | 1.05 (0.34 to 3.22) | ||
| 1 (n=50) | 0 (0%) | 9 (50.0%) | ||||
| >1 (n=24) | 5 (20.8%) | 20 (51.3%) |
*Listed p values are two-tailed.
†ORs were calculated by using the first group in each category as the reference group.
‡DWI changes were assessed in 57 patients who had post-procedure MRIs, including all patients with symptomatic strokes.
ARU, Aspirin Reaction Unit; DWI, diffusion-weighted imaging; PED, Pipeline Embolization Device; PRU, P2Y12 reaction unit.