Comparison of groups with and without successful Thrombolysis in Cerebral Infarction reperfusion
| TICI reperfusion (n=36) | No TICI reperfusion (n=53) | p Value | |
|---|---|---|---|
| Age (years) (median (IQR)) | 60.5 (50.0–73.3) | 68.0 (53.5–79.5) | 0.4 |
| Male (n (%)) | 18/36 (50.0) | 28/53 (52.8) | 0.8 |
| Baseline NIHSS (median (IQR)) | 15.0 (8.3–20.5) | 17.0 (12.5–19.5) | 0.3 |
| Onset to catheterization time (h) (median (IQR)) | 6.0 (4.5–8.7) | 5.4 (3.9–7.0) | 0.2 |
| General anesthesia used (n (%)) | 9/36 (25.0) | 22/53 (41.5) | 0.1 |
| IV tPA used (n (%)) | 20/36 (55.6) | 33/53 (62.3) | 0.5 |
| Patient history (n (%)) | |||
| Atrial fibrillation | 14/36 (38.9) | 16/53 (30.2) | 0.5 |
| Hypercholesterolemia | 15/36 (41.2) | 26/53 (49.1) | 0.5 |
| Diabetes | 8/36 (22.2) | 10/53 (18.9) | 0.7 |
| Antiplatelet use | 9/36 (25.0) | 19/52 (36.5) | 0.3 |
| Anticoagulant use | 5/36 (13.9) | 5/52 (9.6) | 0.5 |
| Radiographic | |||
| Good collaterals (n (%)) | 20/29 (69.0) | 11/41 (26.8) | <0.001 |
| DWI volume (mL) (median (IQR)) | 17.3 (8.3–42.3) | 19.6 (8.0–43.0) | 0.9 |
| PWI volume (mL) (median (IQR)) | 88.9 (58.9–115.9) | 89.2 (44.5–135.6) | 0.9 |
| ICA occlusion (n (%)) | 8/35 (22.9) | 17/47 (36.2) | 0.2 |
| M1 or M2 occlusion (n (%)) | 27/35 (77.1) | 30/47 (63.8) | 0.2 |
| Endovascular treatment modalities used* (n (%)) | |||
| Merci | 24/36 (66.7) | 18/53 (34.0) | <0.01 |
| Penumbra | 14/36 (38.9) | 22/53 (41.5) | 0.8 |
| Other device | 14/36 (38.9) | 13/53 (24.5) | 0.2 |
| Intra-arterial tPA | 14/36 (38.9) | 20/53 (37.7) | 0.9 |
| Hospital site† (n (%)) | <0.001 | ||
| A | 20/26 (76.9) | 6/26 (23.1) | |
| B | 9/24 (37.5) | 15/24 (62.5) | |
| C | 3/9 (33.3) | 6/9 (66.7) | |
| D | 2/11 (18.2) | 9/11 (81.8) | |
| E | 1/6 (16.7) | 5/6 (83.3) | |
| F | 0/5 (0.0) | 5/5 (100.0) | |
| G | 0/4 (0.0) | 4/4 (100.0) | |
| H | 0/3 (0.0) | 3/3 (100.0) | |
*For endovascular treatment used, percentages do not add up to 100% because multiple devices or techniques could be used per patient.
†Data from the ninth site are omitted as only one patient was treated at that site.
DWI, diffusion weighted imaging; ICA, internal carotid artery; NIHSS, National Institutes of Health Stroke Scale; PWI, perfusion weighted imaging; TICI, Thrombolysis in Cerebral Infarction; tPA, tissue plasminogen activator.