Outcomes of mechanical thrombectomy in acute childhood stroke
| Author | NIHSS | Location | Mechanism | DWI | Time to arterial puncture | Device | Thrombolytic | Post-MT antithrombotics | Clinical outcome |
|---|---|---|---|---|---|---|---|---|---|
| Gruber et al2 | NR | R MCA | CE | No preop MRI | 48 h | Guidewire | IA rTPA (0.11 mg/kg) | NR | Asymptomatic at 2 weeks |
| Cognard et al3 | NR | BA | VAD | BA territory | 36 h | Balloon angioplasty | IA UK (900 000 µ) | IV heparin | Asymptomatic at 3 months |
| Grigoriadis et al4 | NR | BA | VAD | BA territory | 44 h | Balloon angioplasty | IA UK (200 000 µ) | ASA, unspecific anticoagulant | Asymptomatic at 9 months |
| Tsivgoulis et al5 | 17 | R ICA | CE | No preop MRI | 3.4 h | Merci | IV (0.9 mg/kg), IA (1.1 µ) tPA | NR | NIHSS 2, mRS 1 at 3 months |
| Grunwald et al6 | 26 | L ICA | CE | L ICA territory | 3 h | Penumbra | None | ASA | NIHSS 0 at 30 days |
| Dubedout et al7 | 20 | BA | Unknown | L Pons | 6 h | CAPTURE | None | Heparin, ASA | NIHSS 0, mRS 0 at 30 days |
| Fink et al8 | 6 | BA | Unknown | R Pons, cerebellum | 4 h | Solitaire | IV tPA (0.6 mg/kg) | NR | Full recovery at 3 months |
| Tatum et al9 | 17 | R ICA | CE | R pons, MCA territory, BG | 4 h | Penumbra | IA tPA (14 mg) | NR | Ped-mRS 3 at 90 days |
| Tatum et al9 | 12 | R MCA | Post-embo | No preop MRI | 8 h | Penumbra | None | NR | Ped-mRS 1 at 90 days |
| Sainz de la Maza et al10 | 18 | R ICA | TCA | R MCA territory | 8 h | Solitaire | None | NR | NIHSS 1, mRS 1 at 3 months |
| Hu et al11 | 16 | L ICA | Unknown | L FTL | NR | Solitaire/ Penumbra | IV tPA (dose not reported) | NR | NIHSS 3 at 6 months |
| Hu et al11 | 17 | R ICA | CE | No preop MRI | NR | Solitaire | None | NR | NIHSS 2 at 3 months |
| Bodey et al12 | 27 | BA | VAD | Bilateral pons, R cerebellum | 36 h | Revive | None | IV heparin | Ped-mRS 3 at 6 months |
| Bodey et al12 | 29 | BA | Dehydration | No preop MRI | 6 h | Solitaire | None | IV heparin | mRS 2 at 6 months |
| Bodey et al12 | 28 | BA | VAD | No preop MRI | 4 h | Solitaire | None | IV heparin. warfarin, ASA | mRS 0 at 6 months |
ASA, aspirin; BA, basilar artery; CE, cardioembolic; DWI, diffusion-weighted imaging; ICA, internal carotid artery; IV, intravenous; MCA, middle cerebral artery; mRS, Modified Rankin Scale; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; NR, not reported; TCA, transient cerebral arteriopathy; tPA, tissue plasminogen activator; VAD, vertebral artery dissection.