Baseline characteristics of patients >60 and 50–60 years of age undergoing surgery for intracranial aneurysm in the matched cohort
| Characteristics | >60 vs <50 | >60 vs 50–60 | ||||||
|---|---|---|---|---|---|---|---|---|
| >60 Years (n=109) (%) | <50 Years (n=109) (%) | p Value | Absolute standardized difference | >60 Years (n=146) (%) | 50–60 Years (n=146) (%) | p Value | Absolute standardized difference | |
| Female | 75.2 | 70.6 | 0.45 | 0.10 | 74.0 | 76.7 | 0.59 | 0.06 |
| Caucasian | 64.2 | 65.1 | 0.89 | 0.02 | 69.6 | 66.7 | 0.61 | 0.06 |
| Admitted from home | 71.6 | 76.2 | 0.44 | 0.10 | 74.0 | 72.6 | 0.79 | 0.03 |
| Smoking status | ||||||||
| Current | 39.5 | 43.1 | 0.86 | 0.08 | 41.1 | 48.6 | 0.43 | 0.15 |
| Previous | 9.2 | 8.3 | 15.1 | 13.0 | ||||
| >2 Drinks a day | 3.7 | 5.5 | 0.52 | 0.09 | 3.4 | 5.5 | 0.39 | 0.10 |
| Dependent functional status | 19.3 | 16.5 | 0.60 | 0.07 | 17.8 | 13.7 | 0.34 | 0.11 |
| ASA classification | ||||||||
| 1+2 | 18.4 | 20.2 | 0.94 | 0.05 | 13.7 | 16.4 | 0.81 | 0.08 |
| 3+4 | 80.7 | 78.9 | 84.9 | 82.2 | ||||
| BMI, kg/m2, mean±SD | 29±7 | 29±8 | 0.52 | 0.01 | 29±7 | 28±7 | 0.34 | 0.08 |
| Cardiopulmonary comorbidities | 20.2 | 13.8 | 0.21 | 0.17 | 28.8 | 25.3 | 0.51 | 0.11 |
| Diabetes mellitus | 4.6 | 4.6 | 1.0 | 0.00 | 15.8 | 15.1 | 0.87 | 0.02 |
| Hypertension requiring medication | 54.1 | 49.5 | 0.50 | 0.09 | 58.9 | 54.1 | 0.41 | 0.10 |
| Cerebrovascular comorbidities | 16.5 | 19.3 | 0.60 | 0.07 | 15.8 | 15.1 | 0.87 | 0.02 |
| Renal comorbidities | 0.9 | 0.0 | 0.32 | 0.14 | 16.7 | 15.1 | 0.01 | 0.09 |
| Cancer-related comorbidities | 1.8 | 0.9 | 0.56 | 0.08 | 2.1 | 0.7 | 0.31 | 0.12 |
| Steroid use for chronic condition | 1.8 | 1.8 | 1.0 | 0.00 | 2.1 | 0.7 | 0.31 | 0.12 |
| Preoperative SIRS or sepsis | 5.5 | 8.3 | 0.42 | 0.11 | 4.8 | 6.2 | 0.61 | 0.06 |
| Bleeding risk factors | 3.8 | 4.9 | 0.70 | 0.05 | 11.6 | 9.6 | 0.57 | 0.08 |
| Prior operation within 30 days | 0.9 | 0.9 | 1.0 | 0.00 | 0.7 | 0.7 | 1.0 | 0.00 |
| Preoperative anemia | 29.4 | 31.2 | 0.77 | 0.05 | 31.5 | 27.4 | 0.44 | 0.08 |
| Abnormal LFT | 14.6 | 14.6 | 1.0 | 0.00 | 13.0 | 9.6 | 0.59 | 0.10 |
| Abnormal WBC | 30.1 | 31.4 | 0.84 | 0.03 | 27.0 | 28.1 | 0.85 | 0.02 |
| Emergency | 24.8 | 25.7 | 0.88 | 0.02 | 25.3 | 19.2 | 0.21 | 0.15 |
| Resident in operating room | 79.8 | 82.6 | 0.60 | 0.07 | 81.5 | 82.2 | 0.88 | 0.02 |
| Intra- and postoperative transfusion | 10.1 | 9.2 | 0.82 | 0.03 | 14.4 | 13.0 | 0.73 | 0.04 |
| Ruptured aneurysm | 39.5 | 41.3 | 0.78 | 0.04 | 34.3 | 34.9 | 0.90 | 0.01 |
| Hunt and Hess grade† | ||||||||
| 1 and 2 | 63.4 | 71.4 | 0.61 | 0.19 | 52.0 | 58.8 | 0.89 | 0.16 |
| 3 | 21.5 | 18.4 | 28.0 | 21.6 | ||||
| 4 | 7.5 | 4.1 | 8.0 | 7.8 | ||||
| 5 | 7.5 | 6.1 | 12.0 | 11.8 | ||||
ASA, American Association of Anesthesiologists; BMI, body mass index; LFT, liver function test; SIRS, systemic inflammatory response syndrome; WBC, white blood cell.