Case No | Age range | Aneurysm type | Location | No of devices | Symptoms | Largest diameter (mm) | Complications | Follow-up (months) | Aneurysm filling (OKM grade) | Adjunctive coiling | Prior treatment | Preoperative mRS | mRS at follow-up |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 60s | Fusiform | Basilar | 2 | Stroke | 29 | Stroke | 18* | Decreased (B3) | No | No | 1 | 6 |
2† | 40s | Saccular | Vertebral | 1 | Headache, fall, prior SAH | 11.5 | None | 28 | Minimal (C3) | Yes | No | 1 | 0 |
3† | 40s | Saccular | Vertebral | 2 | Headache, fall, prior SAH | 7 | Stroke | 25 | None (D1) | Yes | No | 1 | 1 |
4 | 30s | Saccular | Basilar | 2 | Cranial neuropathy, mass effect | 27 | None | 12 | None (D1) | No | No | 3 | 1 |
5 | 50s | Saccular | Vertebral | 1 | Headache | 12 | None | 6 | None (D1) | Yes | No | 1 | 0 |
6 | 50s | Fusiform | Basilar | 5 | Mass effect, stroke | 29 | Non-compliance, stroke | 9‡ | None (D1), due to thrombosis¶ | No | No | 3 | 5 |
7 | 60s | Saccular | PCA | 1 | Recurrence | 11 | Acute stent thrombosis | 3.5§ | Minimal (C3) | No (previously) | Yes | 0 | 1 |
Average | 51.4 | 2 | 18.1 | 14.5 |
*Last imaging follow-up was at 1 month (with an mRS of 4), but the patient died about 18 months after his flow diverter placement.
†Please note that case Nos 2 and 3 are the same patient, whose two aneurysms in different locations were treated separately, 3 months apart.
‡Last imaging follow-up was at 4.5 months, but the patient was still alive 9 months after the procedure.
¶No evidence of residual aneurysm filling due to complete thrombosis of the entire Pipeline construct secondary to medication non-compliance. (Please see text for further explanation of each case.).
§The patient has not yet had 6-month follow-up angiography.
mRS, modified Rankin score; OKM, O'Kelly-Marotta; PCA, posterior cerebral artery; SAH, subarachnoid hemorrhage.