Characteristics | ICA and M1 (N=200)1 | Standard (N=51)2 | Merci (N=77)3 | Penumbra (N=39)4 |
---|---|---|---|---|
*Age, median (min–max) | 69.5 (24–83) | 67 (32–83) | 72 (28–82) | 68 (31–83) |
Male (%) | 97 (48.5) | 25 (49) | 40 (51.9) | 20 (51.3) |
Black/African American/African Canadian (%) | 15 (7.5) | 6 (11.8) | 7 (9.1) | 1 (2.6) |
Hispanic or Latino (%) | 1 (0.5) | 0 (0) | 0 (0) | 1 (2.6) |
Baseline NIHSS: median (min-max) | 19 (8–40) | 18 (8–39) | 20 (10–29) | 18 (10–40) |
ASPECTS 8–10 (%) | 82 (41) | 22 (43.1) | 25 (32.5) | 18 (46.2) |
Presumptive stroke location | ||||
Left hemisphere (%) | 103 (51.5) | 30 (58.8) | 36 (46.8) | 20 (51.3) |
Right hemisphere (%) | 96 (48) | 20 (39.2) | 41 (53.2) | 19 (48.7) |
Unknown/multiple (%) | 1 (0.5) | 1 (2) | 0 (0) | 0 (0) |
*Atrial fibrillation (%) | 78 (39) | 14 (27.5) | 37 (48.1) | 17 (43.6) |
History of hypertension (%) | 144 (72) | 34 (66.7) | 62 (80.5) | 27 (69.2) |
History of diabetes (%) | 40 (20) | 13 (25.5) | 17 (22.1) | 4 (10.3) |
History of congestive heart failure (%) | 20 (10) | 4 (7.8) | 9 (11.7) | 5 (12.8) |
History of coronary artery disease (%) | 50 (25) | 10 (19.6) | 25 (32.5) | 9 (23.1) |
History of hyperlipidemia (%) | 89 (44.5) | 23 (45.1) | 39 (50.6) | 16 (41) |
Baseline serum glucose, mean (SD) | 7.5 (3.1) | 8.1 (3.7) | 7.6 (2.8) | 7.3 (3.1) |
*Time from onset to IV tPA initiation (min), mean (SD) | 122.6 (33.9) | 127.3 (32.7) | 131.1 (32.8) | 111.9 (35.3) |
Pre-existing disability | ||||
No symptoms at all (%) | 172 (86) | 46 (90.2) | 64 (83.1) | 34 (87.2) |
No significant disability despite symptoms (%) | 20 (10) | 4 (7.8) | 10 (13) | 3 (7.7) |
Slight disability (%) | 8 (4) | 1 (2) | 3 (3.9) | 2 (5.1) |
Transfer type | ||||
Mother ship (%) | 162 (81) | 40 (78.4) | 58 (75.3) | 35 (89.7) |
Drip and ship (%) | 26 (13) | 8 (15.7) | 11 (14.3) | 3 (7.7) |
Ship and drip (%) | 11 (5.5) | 3 (5.9) | 7 (9.1) | 1 (2.6) |
*Baseline systolic blood pressure (mm Hg), mean (SD) | 144.6 (21.1) | 140.3 (21.2) | 149 (20.5) | 147.1 (21.9) |
Antiplatelet use at baseline (%) | 91 (45.5) | 23 (45.1) | 37 (48.1) | 18 (46.2) |
Statin use at baseline (%) | 64 (32) | 12 (23.5) | 33 (42.9) | 12 (30.8) |
Baseline INR, median (min–max) | 1 (0.9–1.7) | 1 (0.9–1.6) | 1.1 (0.9–1.7) | 1 (0.9–1.4) |
*Imbalanced between Std MC, Merci, and Penumbra groups, p<0.1 1 Includes all endovascular therapy methods. 1 subject missing glucose 2 2 missing ASPECTS score, 1 missing SBP, 1 missing INR 3 3 missing SBP, 1 missing INR, 1 missing transfer type 4 2 missing SBP, 1 missing NIHSS ASPECTS, Alberta Stroke Program Early CT Score; ICA, internal carotid artery; INR, international normalized ratio; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.