Factors associated with favorable outcomes at 3 months in patients with END by multivariate logistic regression analysis
| Model 1, OR (95% CI) | p Value | Model 2, OR (95% CI) | p Value | |
|---|---|---|---|---|
| Rescue IAT | 7.48 (2.32 to 24.11) | 0.001 | 10.9 (3.1 to 38.8) | <0.001 |
| Baseline NIHSS | 0.63 (0.49 to 0.79) | <0.001 | 0.61 (0.48 to 0.79) | <0.001 |
| FAT to visit time | NA | 0.996 (0.992 to 1.000) | 0.03 | |
| Diabetes mellitus | 0.31 (0.15 to 0.64) | 0.002 | 0.31 (0.15 to 0.66) | 0.002 |
| Symptomatic occlusion | 0.40 (0.19 to 0.84) | 0.02 | 0.42 (0.19 to 0.94) | 0.03 |
| ΔEND−NIHSS | 0.73 (0.63 to 0.84) | <0.001 | 0.71 (0.61 to 0.83) | <0.001 |
Model 1: Adjusted for rescue IAT, age, baseline NIHSS scores, diabetes mellitus, symptomatic occlusion, and ΔEND−NIHSS.
Model 2: Adjusted for rescue IAT, age, baseline NIHSS scores, TOAST classification, FAT to visit time, diabetes mellitus, symptomatic occlusion, and ΔEND−NIHSS.
END, early neurological deterioration; FAT, first known abnormal time; IAT, IA therapy; NIHSS, National Institutes of Health Stroke Scale; TOAST, Trial of Org 10172 in Acute Stroke Treatment; ΔEND−NIHSS, numerical difference between NIHSS scores at the time of END and before END.