Patient baseline characteristics
| Characteristics | No CMBs (n=169) | CMBs (n=37) | p Value |
|---|---|---|---|
| Age, years | 65 (18) | 77 (14) | <0.001 |
| Female sex | 95 (56.2%) | 24 (64.9%) | 0.364 |
| Baseline NIHSS, score | 18 (7) | 18 (5) | 0.842 |
| Cardioembolic stroke source | 102 (60.4%) | 26 (70.3%) | 0.350 |
| Systolic blood pressure, mm Hg | 154 (31) | 159 (27) | 0.324 |
| Diastolic blood pressure, mm Hg | 82 (18) | 82 (15) | 0.935 |
| Blood glucose, mg/dL | 135 (51) | 144 (47) | 0.350 |
| Medical history | |||
| Hypertension | 109 (64.5%) | 26 (70.3%) | 0.570 |
| Diabetes mellitus | 30 (17.8%) | 13 (35.1%) | 0.025 |
| Dyslipidemia | 54 (32.0%) | 10 (27.0%) | 0.695 |
| Atrial fibrillation | 66 (39.1%) | 16 (43.2%) | 0.712 |
| Coronary artery disease | 32 (18.9%) | 11 (29.7%) | 0.179 |
| Previous stroke | 29 (17.2%) | 5 (13.5%) | 0.807 |
| Premorbid drugs | |||
| Aspirin | 44 (26.3%) | 11 (29.7%) | 0.685 |
| Clopidogrel | 11 (6.6%) | 2 (5.4%) | 1.000 |
| Warfarin | 25 (15.0%) | 5 (13.5%) | 1.000 |
| Statins | 44 (26.3%) | 15 (40.5%) | 0.108 |
| Antihypertensive drugs | 81 (48.5%) | 21 (56.8%) | 0.468 |
| White matter hyperintensity | 60 (35.9%) | 22 (59.5%) | 0.010 |
| Most proximal occlusion site | |||
| Internal carotid artery | 53 (31.4%) | 10 (27.0%) | 0.696 |
| Middle cerebral artery M1 | 91 (53.8%) | 25 (67.6%) | 0.146 |
| Middle cerebral artery M2 | 12 (7.1%) | 1 (2.7%) | 0.471 |
| Vertebrobasilar artery | 13 (7.7%) | 1 (2.7%) | 0.473 |
| Intravenous tPA failure | 65 (38.5%) | 9 (24.3%) | 0.131 |
| Intra-arterial lytic use | 13 (7.7%) | 3 (8.1%) | 1.000 |
| Mechanical thrombectomy | |||
| Merci Retriever | 131 (77.5%) | 30 (81.1%) | 0.826 |
| Penumbra aspiration | 24 (14.2%) | 3 (8.1%) | 0.426 |
| Stent-retriever | 14 (8.3%) | 4 (10.8%) | 0.538 |
| Intracranial angioplasty or stenting | 14 (8.3%) | 3 (8.1%) | 1.000 |
| Carotid artery stenting | 15 (8.9%) | 1 (2.7%) | 0.314 |
Data are represented as mean (SD) or number (percentage).
CMBs, cerebral microbleeds; NIHSS, National Institutes of Health Stroke Scale; tPA, tissue plasminogen activator.