Studies included in meta-analysis
| Author, Journal, Year | Number of vertebroplasty patients | Number of kyphoplasty patients | Type of anesthesia used | Specialist performing intervention | Study design | Risk of bias |
|---|---|---|---|---|---|---|
| Bae et al, Spine, 2010 | 20 | 20 | NA | Prospective Non-Randomized | Medium | |
| Bozkurt et al, Asian Spine Journal, 2014 | 96 | 200 | Local | Surgeon | Retrospective comparative | High |
| De Negri et al, Clinical Journal Pain, 2007 | 10 | 11 | General | Prospective Non-Randomized | Medium | |
| Dohm et al, American Journal of Neuroradiology, 2014A | 190 | 191 | Local and general | Radiologist and Surgeon | Randomized controlled trial | Low |
| Dong et al, International Orthopaedics, 2009 | 18 | 20 | NA | Surgeon | Retrospective comparative | High |
| Dong et al, International Orthopaedics, 2012 | 35 | 51 | NA | Surgeon | Prospective comparative | Medium |
| Folman et al, Israel Medical Association Journal, 2011 | 14 | 31 | Local | Prospective Non-Randomized | Medium | |
| Foo et al, International Osteoporosis Foundation, 2006 | 20 | 20 | NA | Surgeon | Prospective Non-Randomized | Medium |
| Frankel et al, The Spine Journal, 2007 | 19 | 17 | NA | Surgeon | Retrospective comparative | High |
| Gan et al, Acta Radiologica, 2013 | 38 | 41 | NA | Surgeon | Retrospective comparative | High |
| Garnier et al, Orthopaedics and Traumatology: Surgery and Research, 2012 | 85 | 42 | General | Surgeon | Retrospective comparative | High |
| Grohs et al, Journal of Spinal Disorders and Techniques, 2005 | 23 | 28 | Local and general | Surgeon | Prospective Non-Randomized | Medium |
| Hiwatashi et al, American Journal of Neuroradiology, 2009 | 66 | 40 | Local and moderate sedation | Radiologist | Retrospective comparative | High |
| Kim et al, Journal of Spinal Disorders and Techniques, 2012 | 58 | 45 | Local | Surgeon | Retrospective comparative | High |
| Kumar et al, Operative Neurosurgery, 2010 | 28 | 24 | Local and conscious sedation | Surgeon | Prospective Non-Randomized | Medium |
| Li et al, Journal of Spinal Disorders and Techniques, 2010 | 40 | 45 | General | Surgeon | Prospective Non-Randomized | Medium |
| Liu et al, Osteoporosis International, 2010 | 50 | 50 | General | Randomized controlled trial | Low | |
| Lovi et al, European Spine Journal, 2009 | 118 | 36 | General | Surgeon | Prospective Non-Randomized | Medium |
| Movrin et al, Archives of Orthopaedic and Trauma Surgery, 2010 | 27 | 46 | Local | Surgeon | Prospective Non-Randomized | Medium |
| Omidi-Kashani et al, Journal of Osteoporosis, 2013 | 29 | 29 | Conscious sedation/general | Surgeon | Prospective Non-Randomized | Medium |
| Rollinghoff et al, Minimally Invasive Neurosurgery, 2009 | 40 | 40 | General | Surgeon | Prospective Non-Randomized | Medium |
| Santiago et al, European Journal of Radiology | 30 | 30 | Conscious sedation/general | Radiologist | Prospective Non-Randomized | Medium |
| Schofer et al, Archives of Orthopaedic and Trauma Surgery, 2009 | 35 | 36 | General | Surgeon | Prospective Non-Randomized | Medium |
| Tang et al, Journal of International Medical Research | 58 | 55 | NA | Surgeon | Retrospective Comparative | High |
| Yan et al, Archives of Orthopaedic and Trauma Surgery, 2011 | 94 | 98 | General | Surgeon | Retrospective Comparative | High |
| Yi et al, Journal of Korean Neurosurgery Society, 2007 | 38 | 34 | NA | Surgeon | Retrospective Comparative | High |
| Yokoyama et al, American Journal of Neuroradiology, 2013 | 28 | 38 | Local/general | Surgeon | Retrospective Comparative | High |
| Zhou et al, Chinese Journal of Traumatology, 2008 | 42 | 56 | General/local | Surgeon | Prospective Non-Randomized | Medium |
| Evans et al, under review, 2014 | 56 | 59 | Local/conscious sedation | Radiologist | Randomized Controlled Trial | Low |