Table 1

Comparison of characteristics of patients with positive and negative MCA SVS

MCA SVS
VariableNegativePositivep Value
Age (years)70.96±12.4465.02±12.670.054
Female9 (37.5%)19 (31.1%)0.614
Comorbid conditions
 Hypertension19 (79.2%)37 (60.7%)0.131
 Diabetes mellitus6 (25.0%)6 (9.8%)0.089
 Hyperlipidemia11 (45.8%)23 (37.7%)0.624
Atrial fibrillation 0.667
 First-detected6 (25.0%)12 (19.7%)
 Chronic6 (25.0%)22 (36.1%)
Clinical variables
 NIHSS score9.83±6.5313.23±5.770.021
 Onset to treatment (min)233.83±77.08239.30±80.080.776
 Previous antiplatelet use4 (16.7%)12 (19.7%)1.000
 Glucose (mmol/L)8.03±2.476.82±1.600.009
 Platelet (109/L)199.08±64.84173.11±61.310.087
 INR1.094±0.1161.038±0.0800.013
Radiologic data
 Baseline infarct volume (mL)33.6±58.634.1±46.90.208*
 M1 occlusion19 (79.2%)42 (68.9%)0.428
Hemorrhagic transformation0.683
 HI5 (20.8%)19 (31.1%)
 PH3 (12.5%)7 (11.5%)
 sICH1 (4.2%)2 (3.3%)1.000
 Recanalization13 (54.2%)29 (47.5%)0.635
 Poor outcome, mRS ≥313 (54.2%)37 (60.7%)0.630
  • *Mann-Whitney U test.

  • HI, hemorrhagic infarction; INR, international normalized ratio; MCA, middle cerebral artery; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PH, parenchymal hemorrhage; sICH, symptomatic intracranial hemorrhage; SVS, susceptibility vessel sign.